Elersek Tina, Kosi Gorazd, Turk Tom, Pohleven Franc, Sepcic Kristina
National Institute of Biology, Ljubljana, Slovenia.
Biofouling. 2008;24(2):137-43. doi: 10.1080/08927010801935745.
Polymeric alkylpyridinium salts (poly-APS) isolated from the marine sponge Reniera sarai act as antifouling and anticholinesterase agents. They also show moderate haemolytic and cytotoxic activities against different cell lines. The haemolytic activity of poly-APS is due to their detergent-like structure and behaviour in aqueous solutions. In this work, the lytic activity of poly-APS against freshwater and marine algae, and inhibitory effects on wood decay fungi, were investigated. The results show that poly-APS inhibit the proliferation and movements of susceptible algae. Effects of poly-APS were time- and concentration-dependent and differed between various algal species. No growth inhibition effects were observed towards the examined wood fungi.
从海洋海绵Reniera sarai中分离出的聚合烷基吡啶盐(poly-APS)具有防污和抗胆碱酯酶作用。它们对不同细胞系还表现出中等程度的溶血和细胞毒性活性。poly-APS的溶血活性归因于其在水溶液中类似洗涤剂的结构和行为。在这项研究中,研究了poly-APS对淡水和海洋藻类的裂解活性以及对木材腐朽真菌的抑制作用。结果表明,poly-APS可抑制易感藻类的增殖和运动。poly-APS的作用具有时间和浓度依赖性,并且在不同藻类物种之间存在差异。未观察到对所检测木材真菌的生长抑制作用。