Bhar Sunil S, Gelfand Lois A, Schmid Sabine P, Gallop Robert, DeRubeis Robert J, Hollon Steven D, Amsterdam Jay D, Shelton Richard C, Beck Aaron T
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.
J Affect Disord. 2008 Sep;110(1-2):161-6. doi: 10.1016/j.jad.2007.12.227. Epub 2008 Feb 13.
The authors examined the patterns of improvement in cognitive and vegetative symptoms of major depression in individuals treated with cognitive therapy (CT) or pharmacotherapy (PT).
Outpatients diagnosed with major depressive disorder (n=180) were randomized to receive either CT or PT. Cognitive and vegetative symptoms of major depression were measured by the Beck Depression Inventory-II at baseline and regularly throughout 16 weeks of treatment.
Multivariate hierarchical linear modeling demonstrated the same patterns of change over time for cognitive and vegetative symptoms within CT and within PT.
Self-report measures may not be sufficiently specific to capture subtle differences in improvements between vegetative and cognitive symptoms.
These results are consistent with Beck's [Beck, A.T., 1984, November. Cognition and theory [Letter to the editor]. Arch. Gen. Psychiatry 41, 1112-1114.] hypothesis that CT and PT have a similar site of action, which when targeted, results in changes in both cognitive and vegetative features.
作者研究了接受认知疗法（CT）或药物疗法（PT）治疗的个体中，重度抑郁症认知症状和躯体症状的改善模式。
将诊断为重度抑郁症的门诊患者（n = 180）随机分为接受CT或PT治疗。在基线时以及整个16周的治疗过程中，通过贝克抑郁量表第二版（Beck Depression Inventory-II）测量重度抑郁症的认知症状和躯体症状。
多变量分层线性模型显示，CT组和PT组内认知症状和躯体症状随时间的变化模式相同。
自我报告测量方法可能不够具体，无法捕捉躯体症状和认知症状改善方面的细微差异。
这些结果与贝克[贝克，A.T.，1984年11月。认知与理论[致编辑的信]。《普通精神病学文献》41，1112 - 1114。]的假设一致，即CT和PT具有相似的作用位点，当针对该位点时，会导致认知和躯体特征的改变。
