Marwaha Steven, Johnson Sonia, Bebbington Paul, Angermeyer Matthias C, Brugha Traolach, Azorin Jean-Michel, Kilian Reinhold, Kornfeld Asa, Toumi Mondher
Department of Mental Health Sciences, Royal Free and University College London Medical School, University College London, London, United Kingdom.
J Nerv Ment Dis. 2008 Feb;196(2):87-94. doi: 10.1097/NMD.0b013e318162aa9c.
Quality of life (QOL) is an important outcome for people with schizophrenia, but most previous studies of its correlates have had small sample sizes or explored a limited number of variables. We conducted an analysis of the baseline data from the European Schizophrenia Cohort (EuroSC) study, a naturalistic investigation of people with schizophrenia living in France, Germany, and the United Kingdom (N = 1208). German participants had the highest subjective QOL. Country of residence, depression, accommodation status, and employment were the most important factors in explaining subjective QOL. Many correlates of subjective QOL in people with schizophrenia were similar to those in the general population. Many of the factors important in explaining subjective QOL in people with schizophrenia are not readily amenable to change. Differences in mental health service provision in the United Kingdom and Germany may in part explain variations in the QOL of people with schizophrenia resident there.
生活质量（QOL）是精神分裂症患者的一项重要预后指标，但此前大多数关于其相关因素的研究样本量较小，或者仅探讨了有限数量的变量。我们对欧洲精神分裂症队列（EuroSC）研究的基线数据进行了分析，该研究是一项针对生活在法国、德国和英国的精神分裂症患者的自然主义调查（N = 1208）。德国参与者的主观生活质量最高。居住国家、抑郁、住宿状况和就业是解释主观生活质量的最重要因素。精神分裂症患者主观生活质量的许多相关因素与普通人群相似。许多对解释精神分裂症患者主观生活质量很重要的因素不易改变。英国和德国心理健康服务提供方面的差异可能部分解释了居住在那里的精神分裂症患者生活质量的差异。
