• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠胸腺中含血管活性肠多肽、乙酰胆碱酯酶和儿茶酚胺的神经分布特征鉴定。

Identification of neural profiles containing vasoactive intestinal polypeptide, acetylcholinesterase and catecholamines in the rat thymus.

作者信息

al-Shawaf A A, Kendall M D, Cowen T

机构信息

Department of Biochemistry, U.M.D.S., London.

出版信息

J Anat. 1991 Feb;174:131-43.

PMID:1827784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1256049/
Abstract

Sympathetic and parasympathetic innervation of the rat thymus is described using immunohistochemical, fluorescence histochemical and histochemical methods. Sympathetic innervation was found to enter the gland with the vasculature and to be distributed mainly in the subcapsular and corticomedullary junctional areas of the cortex. The parasympathetic innervation was also found to enter the gland with the vasculature, but was distributed to both cortex and medulla. Acetylcholinesterase-positive staining cells were seen in the medulla. Ideas about the function of thymus innervation are discussed.

摘要

采用免疫组织化学、荧光组织化学和组织化学方法描述了大鼠胸腺的交感神经和副交感神经支配。发现交感神经支配随血管进入腺体,主要分布在皮质的被膜下和皮质髓质交界区域。还发现副交感神经支配也随血管进入腺体,但分布于皮质和髓质。在髓质中可见乙酰胆碱酯酶阳性染色细胞。文中讨论了关于胸腺神经支配功能的观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/cf0a7db2a094/janat00036-0142-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/d65d6944d095/janat00036-0136-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/8cc26517c81f/janat00036-0138-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/476db5141f65/janat00036-0139-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/38f677abaa49/janat00036-0140-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/cf0a7db2a094/janat00036-0142-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/d65d6944d095/janat00036-0136-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/8cc26517c81f/janat00036-0138-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/476db5141f65/janat00036-0139-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/38f677abaa49/janat00036-0140-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8468/1256049/cf0a7db2a094/janat00036-0142-a.jpg

相似文献

1
Identification of neural profiles containing vasoactive intestinal polypeptide, acetylcholinesterase and catecholamines in the rat thymus.大鼠胸腺中含血管活性肠多肽、乙酰胆碱酯酶和儿茶酚胺的神经分布特征鉴定。
J Anat. 1991 Feb;174:131-43.
2
Parasympathetic innervation of cutaneous blood vessels by vasoactive intestinal polypeptide-immunoreactive and acetylcholinesterase-positive nerves: histochemical and experimental study on rat lower lip.血管活性肠肽免疫反应阳性和乙酰胆碱酯酶阳性神经对皮肤血管的副交感神经支配:大鼠下唇的组织化学和实验研究
Neuroscience. 1988 Apr;25(1):353-62. doi: 10.1016/0306-4522(88)90031-0.
3
Innervation of the rat thymus gland.大鼠胸腺的神经支配。
Brain Behav Immun. 1991 Mar;5(1):9-28. doi: 10.1016/0889-1591(91)90004-t.
4
Interrelation of peptidergic innervation with mast cells and ED1-positive cells in rat thymus.大鼠胸腺中肽能神经支配与肥大细胞及ED1阳性细胞的相互关系。
Brain Behav Immun. 1991 Mar;5(1):55-72. doi: 10.1016/0889-1591(91)90007-w.
5
Spatial distribution of nerve processes and beta-adrenoreceptors in the rat atrioventricular node.大鼠房室结中神经突起和β-肾上腺素能受体的空间分布。
J Anat. 1998 May;192 ( Pt 4)(Pt 4):517-28. doi: 10.1046/j.1469-7580.1998.19240517.x.
6
Parasympathetic innervation of the rat thymus during first life period: histochemical and biochemical study.大鼠生命早期胸腺的副交感神经支配:组织化学与生物化学研究
Thymus. 1992 May;19(3):173-82.
7
Developmental regulation of parasympathetic nerve density by sympathetic innervation in the tarsal smooth muscle of the rat.大鼠睑板平滑肌中交感神经支配对副交感神经密度的发育调节
Neuroscience. 1992 Jul;49(1):229-36. doi: 10.1016/0306-4522(92)90091-f.
8
Absence of cholinergic sympathetic innervation from limb muscle vasculature in rats and mice.大鼠和小鼠肢体肌肉血管系统中胆碱能交感神经支配的缺失。
Auton Neurosci. 2000 Aug 14;82(3):97-108. doi: 10.1016/S0165-1838(00)00094-1.
9
Vasoactive intestinal polypeptide (VIP) innervation of rat spleen, thymus, and lymph nodes.大鼠脾脏、胸腺和淋巴结的血管活性肠肽(VIP)神经支配。
Peptides. 1997;18(8):1139-49. doi: 10.1016/s0196-9781(97)00075-2.
10
Castration of sexually immature rats affects sympathetic innervation of the adult thymus.对性未成熟大鼠进行阉割会影响成年大鼠胸腺的交感神经支配。
Neuroimmunomodulation. 2000;7(2):59-67. doi: 10.1159/000026421.

引用本文的文献

1
Non-Epithelial Thymic Stromal Cells: Unsung Heroes in Thymus Organogenesis and T Cell Development.非上皮性胸腺基质细胞:胸腺器官发生和 T 细胞发育中的无名英雄。
Front Immunol. 2021 Jan 14;11:620894. doi: 10.3389/fimmu.2020.620894. eCollection 2020.
2
Thymus and aging: morphological, radiological, and functional overview.胸腺与衰老:形态学、放射学及功能概述
Age (Dordr). 2014 Feb;36(1):313-51. doi: 10.1007/s11357-013-9564-5. Epub 2013 Jul 23.
3
RETRACTED: Intrinsic innervation and dopaminergic markers after experimental denervation in rat thymus.

本文引用的文献

1
A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES.一种用于胆碱酯酶的“直接显色”硫代胆碱法。
J Histochem Cytochem. 1964 Mar;12:219-21. doi: 10.1177/12.3.219.
2
Two selective inhibitors of cholinesterase.两种胆碱酯酶选择性抑制剂。
Biochem J. 1953 Jul;54(4):695-700.
3
Brain stem projections of sensory and motor components of the vagus complex in the cat: I. The cervical vagus and nodose ganglion.猫迷走神经复合体感觉和运动成分的脑干投射:I. 颈迷走神经和结状神经节。
撤回:实验性去神经支配后大鼠胸腺的内在神经支配和多巴胺能标志物。
Eur J Histochem. 2010 Apr 15;54(2):e17. doi: 10.4081/ejh.2010.e17.
4
Carboxypeptidase E, an essential element of the regulated secretory pathway, is expressed and partially co-localized with chromogranin A in chicken thymus.羧肽酶E是调节性分泌途径的重要组成部分,在鸡胸腺中表达,并与嗜铬粒蛋白A部分共定位。
Cell Tissue Res. 2009 Sep;337(3):371-9. doi: 10.1007/s00441-009-0830-x. Epub 2009 Jul 15.
5
Sympathetic modulation of immunity: relevance to disease.免疫的交感神经调节:与疾病的相关性。
Cell Immunol. 2008 Mar-Apr;252(1-2):27-56. doi: 10.1016/j.cellimm.2007.09.005. Epub 2008 Mar 4.
6
Characterization of thymocyte phenotypic alterations induced by long-lasting beta-adrenoceptor blockade in vivo and its effects on thymocyte proliferation and apoptosis.体内长期β-肾上腺素能受体阻断诱导的胸腺细胞表型改变及其对胸腺细胞增殖和凋亡的影响
Mol Cell Biochem. 2006 Apr;285(1-2):87-99. doi: 10.1007/s11010-005-9059-5. Epub 2006 Feb 14.
7
Studies on rat and human thymus to demonstrate immunoreactivity of calcitonin gene-related peptide, tyrosine hydroxylase and neuropeptide Y.对大鼠和人类胸腺进行研究,以证明降钙素基因相关肽、酪氨酸羟化酶和神经肽Y的免疫反应性。
J Anat. 1997 Oct;191 ( Pt 3)(Pt 3):441-50. doi: 10.1046/j.1469-7580.1997.19130441.x.
8
The effects of pregnancy on the mouse thymic epithelium.妊娠对小鼠胸腺上皮的影响。
Cell Tissue Res. 1994 Feb;275(2):309-18. doi: 10.1007/BF00319429.
9
Characterization of ATP receptor responsible for the activation of phospholipase A2 and stimulation of prostaglandin E2 production in thymic epithelial cells.负责激活胸腺上皮细胞中磷脂酶A2并刺激前列腺素E2产生的ATP受体的特性研究。
Biochem J. 1995 Jun 1;308 ( Pt 2)(Pt 2):399-404. doi: 10.1042/bj3080399.
10
The noradrenergic innervation of the rat thymus during pregnancy and in the post partum period.大鼠孕期及产后胸腺的去甲肾上腺素能神经支配
J Anat. 1994 Dec;185 ( Pt 3)(Pt 3):617-25.
J Comp Neurol. 1980 Sep 15;193(2):435-65. doi: 10.1002/cne.901930210.
4
Central origins of cranial nerve parasympathetic neurons in the rat.大鼠颅神经副交感神经元的中枢起源
J Comp Neurol. 1980 Mar 15;190(2):373-94. doi: 10.1002/cne.901900211.
5
Innervation of the thymus gland by brain stem and spinal cord in mouse and rat.小鼠和大鼠中脑干和脊髓对胸腺的神经支配。
Am J Anat. 1981 Oct;162(2):157-66. doi: 10.1002/aja.1001620207.
6
PGP 9.5--a new marker for vertebrate neurons and neuroendocrine cells.PGP 9.5——一种脊椎动物神经元和神经内分泌细胞的新标志物。
Brain Res. 1983 Nov 14;278(1-2):224-8. doi: 10.1016/0006-8993(83)90241-x.
7
Interaction of vasoactive intestinal peptide with mouse lymphocytes: specific binding and the modulation of mitogen responses.血管活性肠肽与小鼠淋巴细胞的相互作用:特异性结合及对有丝分裂原反应的调节
J Immunol. 1984 Jan;132(1):417-23.
8
Autonomic nervous system innervation of thymic-related lymphoid tissue in wildtype and nude mice.野生型和裸鼠胸腺相关淋巴组织的自主神经系统支配
J Comp Neurol. 1984 Sep 1;228(1):57-68. doi: 10.1002/cne.902280107.
9
Substance P hydrolysis by human serum cholinesterase.人血清胆碱酯酶对P物质的水解作用。
J Neurochem. 1982 Jul;39(1):106-10. doi: 10.1111/j.1471-4159.1982.tb04707.x.
10
Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: functional significance of coexisting transmitters for vasodilation and secretion.外分泌腺胆碱能神经元中的血管活性肠肽:共存递质对血管舒张和分泌的功能意义。
Proc Natl Acad Sci U S A. 1980 Mar;77(3):1651-5. doi: 10.1073/pnas.77.3.1651.