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眼部黑素细胞肿瘤

Ocular melanocytic neoplasia.

作者信息

Finn Michael, Krohne Sheryl, Stiles Jean

机构信息

Purdue University.

出版信息

Compend Contin Educ Vet. 2008 Jan;30(1):19-25; quiz 26.

Abstract

Tumors of melanocytic origin in ocular tissues are relatively uncommon in dogs and cats, and although many are benign, some have a high potential for metastasis. In addition, even small ocular masses can be significant due to their potential vision-threatening sequelae. Such tumors may occur on the eyelids, on the conjunctival surface, along the limbus, or within the uveal tract. While several similarities exist among these tumors, the prognosis and recommended treatment options vary based on the species affected as well as the location, extent, and histologic characteristics of the tumor. This article reviews the clinical presentation, biologic behavior, and treatment options for eyelid, conjunctival, limbal (epibulbar), and uveal tumors of melanocytic origin in dogs and cats.

摘要

眼组织中起源于黑素细胞的肿瘤在犬猫中相对不常见,尽管许多是良性的,但有些具有很高的转移潜力。此外,即使是小的眼部肿块也可能很严重,因为它们可能会产生威胁视力的后遗症。此类肿瘤可发生于眼睑、结膜表面、角膜缘或葡萄膜内。虽然这些肿瘤之间存在一些相似之处,但预后和推荐的治疗方案因受影响的物种以及肿瘤的位置、范围和组织学特征而异。本文综述了犬猫眼睑、结膜、角膜缘(眼球表面)和葡萄膜黑素细胞起源肿瘤的临床表现、生物学行为和治疗方案。

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