Wémeau J L
Service de Clinique Médicale, U.S.N.A. CHR, Lille.
Presse Med. 1991 Apr 6;20(13):601-6.
Endocrine and immune system explorations, systematically performed at the end of pregnancy for the last 15 years, have shown that in about 5 percent of women delivery is followed by thyroid dysfunction and goitrogenic episodes due to a painless or silent thyroiditis. In genetically predisposed subjects, this pathology is the expression of a hitherto asymptomatic chronic lymphocytic thyroiditis revealed by the generalized autoimmunity rebound that is characteristic of the postpartum period. Usually benign and transient, the thyroiditis may recur during subsequent pregnancies and eventually result in permanent hypothyroidism.
在过去15年中,于妊娠末期系统性开展的内分泌与免疫系统研究表明,约5%的女性在分娩后会因无痛性或寂静性甲状腺炎出现甲状腺功能障碍和致甲状腺肿发作。在具有遗传易感性的个体中,这种病症是一种迄今无症状的慢性淋巴细胞性甲状腺炎的表现,它由产后特有的全身性自身免疫反弹所揭示。甲状腺炎通常为良性且短暂,可能在后续妊娠期间复发,并最终导致永久性甲状腺功能减退。