Int J Cardiol. 2009 Jul 10;135(3):393-6. doi: 10.1016/j.ijcard.2007.12.026. Epub 2008 Feb 15.
Although all beta blockers appear to be effective in the prevention of postoperative atrial fibrillation (AF) following coronary artery bypass surgery (CABG), carvedilol was found to be much more effective than metoprolol in this respect as the current study clearly delineated. We believe that the ongoing COMPACT trial will answer the question of whether or not carvedilol is more superior than metoprolol to prevent postoperative AF in patients undergoing CABG.
虽然所有β受体阻滞剂在预防冠状动脉旁路移植手术后心房颤动(AF)方面似乎都有效,但正如本研究清楚表明的那样,卡维地洛在这方面比美托洛尔更有效。我们相信,正在进行的 COMPACT 试验将回答卡维地洛是否比美托洛尔更能预防 CABG 术后 AF 的问题。