Poullin P, Lefèvre P
Service d'hémaphérèse et d'autotransfusion, hôpital de la Conception, 13385 Marseille cedex 05, France.
Rev Med Interne. 2008 Apr;29(4):290-6. doi: 10.1016/j.revmed.2007.10.406. Epub 2007 Nov 20.
Therapeutic erythrocytapheresis is a selective red cell-depletion aphaeresis technique.
Using a discontinuous or continuous flow blood cell separator, the technique safely allows quickly and automatically collecting a large volume of red cells. The main obstacle of implementation is a poor peripheral venous access. The procedure is well-tolerated. Polycythemia vera, hereditary hemochromatosis, complicated sickle-cell-disease and retinal venous occlusion are the main clinical applications.
Therapeutic erythrocytapheresis is a more modern and more effective method than the classic patient-bleeding. It has to be preferred in the early treatment of patients with polycythemia vera and hereditary hemochromatosis.
治疗性红细胞单采术是一种选择性红细胞去除单采技术。
使用间断或连续流动血细胞分离仪，该技术能安全、快速且自动地采集大量红细胞。实施的主要障碍是外周静脉通路不佳。该操作耐受性良好。真性红细胞增多症、遗传性血色素沉着症、复杂镰状细胞病和视网膜静脉阻塞是主要临床应用。
治疗性红细胞单采术是一种比传统患者放血更现代、更有效的方法。在真性红细胞增多症和遗传性血色素沉着症患者的早期治疗中应优先选用。
