[Therapeutic erythrocytapheresis: technical aspects and clinical applications].

PURPOSE

Therapeutic erythrocytapheresis is a selective red cell-depletion aphaeresis technique.

CURRENT KNOWLEDGE AND KEY POINT

Using a discontinuous or continuous flow blood cell separator, the technique safely allows quickly and automatically collecting a large volume of red cells. The main obstacle of implementation is a poor peripheral venous access. The procedure is well-tolerated. Polycythemia vera, hereditary hemochromatosis, complicated sickle-cell-disease and retinal venous occlusion are the main clinical applications.

PROSPECT AND PROJECT

Therapeutic erythrocytapheresis is a more modern and more effective method than the classic patient-bleeding. It has to be preferred in the early treatment of patients with polycythemia vera and hereditary hemochromatosis.