明显危及生命的事件与婴儿猝死综合征：危险因素比较

Apparent life-threatening events and sudden infant death syndrome: comparison of risk factors.

作者信息

Esani Nahid, Hodgman Joan E, Ehsani Nazanin, Hoppenbrouwers Toke

机构信息

University of Southern California, Division of Neonatal Medicine, LAC + USC Medical Center, Women's and Children's Hospital, and Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

出版信息

J Pediatr. 2008 Mar;152(3):365-70. doi: 10.1016/j.jpeds.2007.07.054. Epub 2007 Nov 5.

DOI:10.1016/j.jpeds.2007.07.054

PMID:18280841

Abstract

OBJECTIVE

To compare the risk factors of 153 cases of apparent life-threatening event (ALTE) enrolled in the multicenter Collaborative Home Infant Monitoring Evaluation (CHIME) from 1994 to 1998 with the published risk factors for sudden infant death syndrome (SIDS).

STUDY DESIGN

Trained CHIME interviewers gathered histories of infants with ALTE who met the criteria. The following risk factors were analyzed: male predominance, gestational age, low birth weight, very low birth weight, incidence of small for gestational age (SGA), age at the event, multiparity, maternal age, and smoking. Population-based SIDS studies with >100 deaths, focusing on 1 or more pertinent risk factors and carried out during the decade in which CHIME data were collected, were chosen for comparison.

RESULTS

One of the 153 infants with ALTE in this study died during follow-up (0.6%). CHIME ALTE differed significantly from SIDS in 4 respects: fewer infants with low birth weight and SGA at birth, fewer teenage pregnancies, and a younger infant age at ALTE.

CONCLUSIONS

Although a number of risk factors for ALTE are similar to those for SIDS, the differences warrant a separate focus on ALTE beyond that on SIDS.

摘要

目的

比较1994年至1998年纳入多中心协作家庭婴儿监测评估（CHIME）的153例明显危及生命事件（ALTE）的危险因素与已发表的婴儿猝死综合征（SIDS）的危险因素。

研究设计

经过培训的CHIME访视员收集了符合标准的ALTE婴儿的病史。分析了以下危险因素：男性占比、孕周、低出生体重、极低出生体重、小于胎龄儿（SGA）发生率、事件发生时的年龄、多胎妊娠、母亲年龄和吸烟情况。选择在收集CHIME数据的十年期间进行的、以100例以上死亡为基础、关注1个或多个相关危险因素的基于人群的SIDS研究进行比较。