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[以急性呼吸窘迫综合征为表现的慢性嗜酸性粒细胞性肺炎]

[An acute respiratory distress syndrome revealing a chronic eosinophilic pneumonia].

作者信息

Yavchitz A, Binczak M, Meybeck A, Mounier R, Ricard J-D

机构信息

Service de réanimation, hôpital Louis-Mourier, 178, rue des Renouillers, 92701 Colombes cedex, France.

出版信息

Ann Fr Anesth Reanim. 2008 Mar;27(3):237-9. doi: 10.1016/j.annfar.2007.12.013. Epub 2008 Feb 20.

Abstract

Idiopathic chronic eosinophilic pneumonia (ICEP) is one of the idiopathic hypereosinophilic lung diseases. ICEP differs from idiopathic acute eosinophilic pneumonia (IAEP) by its progressive onset, and the absence of severe hypoxemia. We report a case of acute respiratory distress syndrome revealing an ICEP, which needed a 48h of mechanical ventilation. ICEP is an exceptional cause of acute respiratory failure. Symptoms always improve with corticosteroids. But relapses are frequent after stopping corticosteroid treatment, as well as the occurrence of severe asthma. Distinction between ICEP and IAEP is essential because of its impact on treatment duration and on prognosis.

摘要

特发性慢性嗜酸性粒细胞性肺炎(ICEP)是特发性嗜酸性粒细胞增多性肺病之一。ICEP与特发性急性嗜酸性粒细胞性肺炎(IAEP)不同,其起病呈进行性,且无严重低氧血症。我们报告一例急性呼吸窘迫综合征病例,该病例显示为ICEP,需要进行48小时的机械通气。ICEP是急性呼吸衰竭的罕见病因。症状通常会随着使用皮质类固醇而改善。但停用皮质类固醇治疗后复发频繁,严重哮喘的发生也很常见。区分ICEP和IAEP至关重要,因为这会影响治疗持续时间和预后。

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