Fujimura N
Department of Internal Medicine, National Hira Hospital.
Nihon Rinsho. 1993 Mar;51(3):771-8.
Pulmonary eosinophilia is a disease entity which is characterized by an increase of eosinophils in the bronchoalveolar lavage fluid or in tissue. While there are several disease states encountered in pulmonary eosinophilia, some have a definite cause and diagnosis, while others are of unknown etiology. The diagnosis of idiopathic eosinophilic pneumonia is given when other pulmonary eosinophilia with known cause and diagnosis are excluded. Simple pulmonary eosinophilia and chronic eosinophilic pneumonia are well established disease entities, but recent papers have clarified a new concept of acute eosinophilic pneumonia. In this article, the clinical features of three idiopathic eosinophilic pneumonias simple pulmonary eosinophilia as a self-limiting lung infiltrates, chronic eosinophilic pneumonia as a disease with longstanding symptoms requiring steroids administration and a tendency to relapse, and acute eosinophilic pneumonia as an acute respiratory distress which responds dramatically to steroids administration and without relapse after discontinuation of therapy are discussed.
肺嗜酸性粒细胞增多症是一种以支气管肺泡灌洗液或组织中嗜酸性粒细胞增多为特征的疾病实体。虽然在肺嗜酸性粒细胞增多症中会遇到多种疾病状态,但有些有明确的病因和诊断,而另一些病因不明。当排除其他已知病因和诊断的肺嗜酸性粒细胞增多症时,即可诊断为特发性嗜酸性粒细胞性肺炎。单纯性肺嗜酸性粒细胞增多症和慢性嗜酸性粒细胞性肺炎是已明确的疾病实体,但最近的论文阐明了急性嗜酸性粒细胞性肺炎的新概念。本文讨论了三种特发性嗜酸性粒细胞性肺炎的临床特征:单纯性肺嗜酸性粒细胞增多症为自限性肺部浸润,慢性嗜酸性粒细胞性肺炎为具有长期症状、需要使用类固醇治疗且有复发倾向的疾病,急性嗜酸性粒细胞性肺炎为急性呼吸窘迫,对类固醇治疗反应显著且停药后无复发。