Guidi L, Bartoloni C, Pellicanò P, Cappelli A, Cursi F, Pili R, Tricerri A, Patriarca F, Gambassi G
Facoltà di Medicina e Chirurgia, Istituto di Clinica Medica Generale e Terapia Medica, Università Cattolica del Sacro Cuore di Roma.
Clin Ter. 1991 Mar 31;136(6):367-73.
The relationship between cancer and coagulation disorders is widely accepted. Such disorders can contribute to the metastatic spreading of the primary tumor. Aim of our study was to evaluate the alterations of thrombin-antithrombin III complex (TAT) measured by an ELISA plasma assay in a population of 78 patients suffering from various gastrointestinal tumors. We found high levels of TAT in 68.6% of the patients. Our data show that assay of TAT plasma levels may be a useful test in detecting early coagulation disorders in cancer patients.
癌症与凝血功能障碍之间的关系已被广泛认可。此类功能障碍会促使原发性肿瘤发生转移扩散。我们研究的目的是通过酶联免疫吸附测定血浆法评估78例患有各种胃肠道肿瘤患者体内凝血酶 - 抗凝血酶III复合物（TAT）的变化情况。我们发现68.6%的患者TAT水平较高。我们的数据表明，检测血浆TAT水平可能是检测癌症患者早期凝血功能障碍的一项有用检测方法。
