Huang Tsung-Wei, Cheng Po-Wen
Department of Otolaryngology, Far Eastern Memorial Hospital, Taipei, Taiwan.
Arch Otolaryngol Head Neck Surg. 2008 Feb;134(2):141-5. doi: 10.1001/archoto.2007.27.
To assess subjective and objective outcomes in selected patients with obstructive sleep apnea syndrome who underwent microdebrider-assisted extended uvulopalatoplasty (MEUP).
Prospective study.
Tertiary referral center.
Fifty patients with obstructive sleep apnea syndrome who had substantial retropalatal obstruction and more than 10 events per hour on the respiratory disturbance index (RDI) and who underwent MEUP with 6 months of follow-up. Patients with a Friedman palate position of grade 4 and a tonsil size of grade 3 or 4 were excluded.
MEUP was performed in each patient under general anesthesia. The procedure consisted of removal of the redundant mucosa, tissue above the muscular layer of the soft palate, and upper poles of the tonsils using a powered microdebrider.
Postoperative pain was evaluated using a visual analog scale. Before surgery and at 6 months after surgery, subjective outcomes were assessed using the Epworth Sleepiness Scale and the snoring scale, and objective outcomes were assessed using overnight polysomnography variables (RDI, snoring index, and minimal oxygen saturation). Surgical success was defined as achieving a postoperative RDI score of fewer than 20 events per hour and a greater than 50% reduction in the preoperative RDI score.
The mean (SD) visual analog scale scores were 3.9 (1.8) on the first postoperative day and 1.3 (0.9) on the seventh postoperative day. Compared with preoperative scores, postoperative scores statistically significantly improved on the Epworth Sleepiness Scale and on the snoring scale (P < .01 for both). The median RDI score decreased from 37.9 events per hour before surgery to 6.1 events per hour at 6 months after surgery, a statistically significant difference (P < .001). The median minimal oxygen saturation and snoring index scores also improved statistically significantly (P < .001 for both). The surgical success rate was 80% (40 of 50 patients). No postoperative bleeding or long-term velopharyngeal insufficiency was observed in any patient.
MEUP is an effective and safe surgical procedure to improve sleep apnea and snoring in selected patients with obstructive sleep apnea syndrome. The use of the microdebrider in extended uvulopalatoplasty is addressed herein for the first time (to our knowledge).
评估接受微型切割器辅助扩大悬雍垂腭咽成形术(MEUP)的部分阻塞性睡眠呼吸暂停综合征患者的主观和客观疗效。
前瞻性研究。
三级转诊中心。
50例阻塞性睡眠呼吸暂停综合征患者,这些患者存在明显的腭后阻塞,呼吸紊乱指数(RDI)每小时超过10次事件,并接受了MEUP且随访6个月。排除Friedman腭位为4级且扁桃体大小为3级或4级的患者。
每位患者在全身麻醉下进行MEUP。该手术包括使用电动微型切割器切除多余的黏膜、软腭肌层上方的组织以及扁桃体上极。
使用视觉模拟量表评估术后疼痛。在手术前和手术后6个月,使用Epworth嗜睡量表和打鼾量表评估主观疗效,使用整夜多导睡眠图变量(RDI、打鼾指数和最低血氧饱和度)评估客观疗效。手术成功定义为术后RDI评分达到每小时少于20次事件,且术前RDI评分降低超过50%。
术后第1天视觉模拟量表平均(标准差)评分为3.9(1.8),术后第7天为1.3(0.9)。与术前评分相比,术后Epworth嗜睡量表和打鼾量表评分在统计学上有显著改善(两者P <.01)。RDI评分中位数从手术前的每小时37.9次事件降至术后6个月的每小时6.1次事件,差异有统计学意义(P <.001)。最低血氧饱和度中位数和打鼾指数评分在统计学上也有显著改善(两者P <.001)。手术成功率为80%(50例患者中的40例)。未观察到任何患者术后出血或长期腭咽闭合不全。
MEUP是改善部分阻塞性睡眠呼吸暂停综合征患者睡眠呼吸暂停和打鼾的一种有效且安全的手术方法。据我们所知,本文首次探讨了微型切割器在扩大悬雍垂腭咽成形术中的应用。