Akbulut Metin, Soysal Mehmet E, Duzcan S Ender
Department of Pathology, Pamukkale University School of Medicine, Morfoloji Binasi, Kinikli 20070, Denizli, Turkey.
Arch Gynecol Obstet. 2008 Sep;278(3):291-3. doi: 10.1007/s00404-008-0580-0. Epub 2008 Feb 19.
Lipoleiomyoma is a rare and easily recognized, benign uterine fatty tumor, composed of an admixture of mature adipocytes and smooth-muscle cells. They may associate with metabolic disorders and rarely reach giant size.
We report a case of symptomatic giant lipoleiomyoma of the uterine corpus that may be associated with diabetes mellitus and hypothyroidism.
Lipoleiomyoma must be thought in the differential diagnosis of the giant uterine tumors and should be removed when diagnosed, because malignancy cannot otherwise be excluded. Also the peculiar features of this giant neoplasm, histogenesis, concomitant metabolic disorders and the diagnostic methods are discussed.
脂肪平滑肌瘤是一种罕见且易于识别的子宫良性脂肪性肿瘤,由成熟脂肪细胞和平滑肌细胞混合组成。它们可能与代谢紊乱相关,很少发展到巨大尺寸。
我们报告一例子宫体部有症状的巨大脂肪平滑肌瘤病例,该病例可能与糖尿病和甲状腺功能减退有关。
在巨大子宫肿瘤的鉴别诊断中必须考虑脂肪平滑肌瘤,确诊后应予以切除,因为否则无法排除恶性肿瘤。此外,还讨论了这种巨大肿瘤的特殊特征、组织发生、伴随的代谢紊乱及诊断方法。