Palmquist Anders, Jarmar Tobias, Emanuelsson Lena, Brånemark Rickard, Engqvist Håkan, Thomsen Peter
Department of Biomaterials, Sahlgrenska Academy at Göteborg University, Göteborg, Sweden.
Acta Orthop. 2008 Feb;79(1):78-85. doi: 10.1080/17453670710014806.
Bone-anchored titanium implants have been used for anchorage of amputation prostheses for more than one and a half decades. Histo-logical and ultrastructural analyses were performed on a forearm amputation prosthesis after being in use for more than 11 years.
MATERIAL, METHODS AND RESULTS: The implant was retrieved from the ulnar bone after a fatigue fracture of the titanium implant, and was clinically stable at the time of removal. The histological findings showed a large amount of bone within the threads and a high degree of apposition of mineralized bone to the implant surface. Ultrastructural analysis of thin samples prepared by focused ion-beam microscopy revealed an electron-dense layer at the interface and direct apposition of crystalline hydroxyapatite at the implant surface.
Our observations in this retrieval study provide a structural correlate to the functional properties and clinical results of amputation prostheses.
骨锚定钛植入物用于截肢假肢的锚固已有超过十五年的时间。对一个使用了超过11年的前臂截肢假肢进行了组织学和超微结构分析。
材料、方法与结果：在钛植入物发生疲劳骨折后，从尺骨取出该植入物，取出时其在临床上是稳定的。组织学结果显示螺纹内有大量骨组织，矿化骨与植入物表面高度贴合。通过聚焦离子束显微镜制备的薄样本的超微结构分析显示，界面处有一个电子致密层，植入物表面有结晶羟基磷灰石直接贴合。
我们在这项取出研究中的观察结果为截肢假肢的功能特性和临床结果提供了结构上的关联。
