加替沙星对感染巴西诺卡菌的BALB/c小鼠的体内治疗效果。
In vivo therapeutic effect of gatifloxacin on BALB/c mice infected with Nocardia brasiliensis.
作者信息
Daw-Garza Alejandra, Welsh Oliverio, Said-Fernández Salvador, Lozano-Garza Hector Gerardo, Waksman de Torres Noemi, Rocha Norma Cavazos, Ocampo-Candiani Jorge, Vera-Cabrera Lucio
机构信息
Servicio de Dermatología, Hospital Universitario José E González, Monterrey, NL, México.
出版信息
Antimicrob Agents Chemother. 2008 Apr;52(4):1549-50. doi: 10.1128/AAC.00148-08. Epub 2008 Feb 19.
Abstract
In the present work, we evaluated the effect of gatifloxacin on the evolution of experimental murine infection with Nocardia brasiliensis using linezolid as a control. Gatifloxacin was injected subcutaneously at 100 mg/kg body weight every 8 h for 4 weeks. This compound was equally as efficient as linezolid in reducing the production of lesions.
摘要
在本研究中，我们以利奈唑胺作为对照，评估了加替沙星对巴西诺卡菌实验性小鼠感染病程的影响。加替沙星以100mg/kg体重皮下注射，每8小时一次，共4周。该化合物在减少损伤产生方面与利奈唑胺同样有效。
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