Díaz-Marsá M, González Bardanca S, Tajima K, García-Albea J, Navas M, Carrasco J L
Hospital Clínico San Carlos, Madrid, Spain.
Actas Esp Psiquiatr. 2008 Jan-Feb;36(1):39-49.
Borderline personality disorder is a disorder with important social and clinical repercussions, which has been treated mainly by psychotherapy. In recent years, the syndromic analysis of this disorder has allowed us to identify different symptoms capable of being improved with psychopharmacology treatment. Thus, its complex symptomatology could be included in four clinical dimensions: impulsive-aggressive, affective instability, cognitive- perceptive and anxiety-inhibition. Antidepressants, mood stabilizers, antipsychotics, anxiolytics, or more recently omega-3 fatty acids have shown efficacy in the treatment of symptomatic dimensions of this disease. We have reviewed scientific articles (reviews, clinical trials or clinical guidelines) published over the last ten years and have proposed therapeutic algorithms for psychopharmacology management in these patients.
边缘型人格障碍是一种具有重要社会和临床影响的疾病，主要通过心理治疗进行治疗。近年来，对该疾病的综合征分析使我们能够识别出可通过精神药物治疗得到改善的不同症状。因此，其复杂的症状可归纳为四个临床维度：冲动攻击型、情感不稳定型、认知感知型和焦虑抑制型。抗抑郁药、心境稳定剂、抗精神病药、抗焦虑药或最近的ω-3脂肪酸已显示出对该疾病症状维度的治疗效果。我们回顾了过去十年发表的科学文章（综述、临床试验或临床指南），并提出了这些患者精神药物管理的治疗算法。
