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成人多形性肉瘤(所谓的“恶性纤维组织细胞瘤”)的诊断与管理。

Diagnosis and management of pleomorphic sarcomas (so-called "MFH") in adults.

作者信息

Nascimento Alessandra F, Raut Chandrajit P

机构信息

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

出版信息

J Surg Oncol. 2008 Mar 15;97(4):330-9. doi: 10.1002/jso.20972.

Abstract

The existence of "malignant fibrous histiocytoma" ("MFH") as a distinct entity is controversial. Previously accepted as the most common sarcoma affecting adults, it is now known to comprise a heterogeneous group of tumors without a specific known line of differentiation. Reclassification of many tumors in this group afforded better prognostication, but traditional treatments still apply. Pleomorphic soft tissue tumors for which a line of differentiation is debatable are presently categorized as undifferentiated pleomorphic sarcoma.

摘要

“恶性纤维组织细胞瘤”(“MFH”)作为一种独立的实体瘤,其存在存在争议。它曾被认为是影响成年人的最常见肉瘤,现在已知它是一组异质性肿瘤,没有特定的已知分化谱系。对该组中许多肿瘤进行重新分类可提供更好的预后,但传统治疗方法仍然适用。目前,分化谱系存在争议的多形性软组织肿瘤被归类为未分化多形性肉瘤。

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