Nascimento Alessandra F, Raut Chandrajit P
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
J Surg Oncol. 2008 Mar 15;97(4):330-9. doi: 10.1002/jso.20972.
The existence of "malignant fibrous histiocytoma" ("MFH") as a distinct entity is controversial. Previously accepted as the most common sarcoma affecting adults, it is now known to comprise a heterogeneous group of tumors without a specific known line of differentiation. Reclassification of many tumors in this group afforded better prognostication, but traditional treatments still apply. Pleomorphic soft tissue tumors for which a line of differentiation is debatable are presently categorized as undifferentiated pleomorphic sarcoma.
“恶性纤维组织细胞瘤”(“MFH”)作为一种独立的实体瘤,其存在存在争议。它曾被认为是影响成年人的最常见肉瘤,现在已知它是一组异质性肿瘤,没有特定的已知分化谱系。对该组中许多肿瘤进行重新分类可提供更好的预后,但传统治疗方法仍然适用。目前,分化谱系存在争议的多形性软组织肿瘤被归类为未分化多形性肉瘤。