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前纵隔未分化多形性肉瘤：一例报告及文献复习

Undifferentiated pleomorphic sarcoma in the anterior mediastinum: a case report and literature review.

作者信息

Wang Luyao, Xie Anyu, Ke Luqin, Jia Pingfan, Li Yuru, Guo Xing

机构信息

Department of Radiology, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, China.

出版信息

Front Oncol. 2024 Oct 15;14:1445149. doi: 10.3389/fonc.2024.1445149. eCollection 2024.

DOI:10.3389/fonc.2024.1445149
PMID:39474109
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11518729/
Abstract

Primary undifferentiated high-grade pleomorphic sarcoma (UPS) in the mediastinum is exceptionally rare. This paper reports a unique case of anterior mediastinal UPS in an 84-year-old Asian male presenting with recurrent upper respiratory tract infections and upper abdominal discomfort. Imaging via CT and MRI suggested an invasive thymoma, but postoperative pathology confirmed UPS. Despite radical surgery, local recurrence occurred within three months, and palliative radiotherapy was ineffective. This case provides the first comprehensive imaging data of UPS in the anterior mediastinum, aiming to improve diagnostic accuracy for clinicians and radiologists by summarizing imaging features across various modalities.

摘要

原发性纵隔未分化高级别多形性肉瘤（UPS）极为罕见。本文报告了一例84岁亚洲男性前纵隔UPS的独特病例，该患者表现为反复上呼吸道感染和上腹部不适。CT和MRI成像提示为侵袭性胸腺瘤，但术后病理确诊为UPS。尽管进行了根治性手术，但患者在三个月内出现局部复发，姑息性放疗无效。本病例提供了前纵隔UPS的首个全面影像数据，旨在通过总结各种检查方式的影像特征，提高临床医生和放射科医生的诊断准确性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/b38b7d8fdd0e/fonc-14-1445149-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/fc7877304534/fonc-14-1445149-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/8bf09111d6f0/fonc-14-1445149-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/c1c154281b08/fonc-14-1445149-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/f88ce5a04549/fonc-14-1445149-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/eb00d2486e96/fonc-14-1445149-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/5cec0f249e70/fonc-14-1445149-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/8ccecc6938d4/fonc-14-1445149-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/ef4442dd29e5/fonc-14-1445149-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/b38b7d8fdd0e/fonc-14-1445149-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/fc7877304534/fonc-14-1445149-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/8bf09111d6f0/fonc-14-1445149-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/c1c154281b08/fonc-14-1445149-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/f88ce5a04549/fonc-14-1445149-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/eb00d2486e96/fonc-14-1445149-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/5cec0f249e70/fonc-14-1445149-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/8ccecc6938d4/fonc-14-1445149-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/ef4442dd29e5/fonc-14-1445149-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742b/11518729/b38b7d8fdd0e/fonc-14-1445149-g009.jpg

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Pleomorphic undifferentiated sarcoma of the mediastinal thymus: A case report and literature review.纵隔胸腺多形性未分化肉瘤：一例报告及文献复习
Oncol Lett. 2023 Jun 1;26(1):306. doi: 10.3892/ol.2023.13892. eCollection 2023 Jul.
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Unveiling the Genomic Basis of Chemosensitivity in Sarcomas of the Extremities: An Integrated Approach for an Unmet Clinical Need.
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