Bernard P, Bedane C, Catanzano G, Robbe J, Bonnetblanc J M
Department of Dermatology, CHU Dupuytren, Limoges, France.
Dermatologica. 1991;182(2):115-8.
A 74-year-old woman developed a generalized pustular dermatosis with erythema-multiforme-like and vesiculobullous lesions 10 days after beginning a treatment by nadoxolol. Despite the clinical polymorphism of the eruption, histology constantly revealed the presence of subcorneal pustules, even within the epidermis overlying subepidermal bullae. The eruption spontaneously healed after discontinuation of nadoxolol.
一名74岁女性在开始使用纳多洛尔治疗10天后出现了伴有多形红斑样和水疱大疱性损害的泛发性脓疱性皮肤病。尽管皮疹具有临床多形性，但组织学检查始终显示存在角层下脓疱，即使在表皮下大疱上方的表皮内也是如此。停用纳多洛尔后，皮疹自行愈合。
