台湾地区中国人的磷酸葡萄糖变位酶-1多态性

Phosphoglucomutase-1 polymorphism among Chinese in Taiwan.

作者信息

Lin-Chu M, Loo J H, Hayward M A

机构信息

Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan, R.O.C.

出版信息

Hum Hered. 1991;41(1):22-5. doi: 10.1159/000153969.

DOI:10.1159/000153969

PMID:1828778

Abstract

Phosphoglucomutase-1 (PGM1) phenotyping of 1,128 Chinese blood donors was performed by thin-layer isoelectric focusing on agarose. The PGM1 gene frequencies were: 1A, 0.6005; 1B, 0.1500; 2A, 0.1510; 2B, 0.0973, and rare variants, 0.0058. The rare variants found in this series were PGM1 W21, W2, W3, W6 and W9 (or W10) with PGM1 W21 being the most common variant among Chinese with a phenotype frequency of 0.8%.

摘要

采用琼脂糖薄层等电聚焦法对1128名中国献血者进行磷酸葡萄糖变位酶-1（PGM1）表型分析。PGM1基因频率分别为：1A，0.6005；1B，0.1500；2A，0.1510；2B，0.0973，稀有变异型，0.0058。本研究系列中发现的稀有变异型为PGM1 W21、W2、W3、W6和W9（或W10），其中PGM1 W21是中国人中最常见的变异型，表型频率为0.8%。