Obeid Omar, Elfakhani Manal, Hlais Sani, Iskandar Michel, Batal Malek, Mouneimne Youssef, Adra Nada, Hwalla Nahla
Department of Nutrition and Food Science, Faculty of Agricultural and Food Sciences, American University of Beirut, P.O. Box 11-0236, Riad El Solh, Beirut, 1107-2020, Lebanon.
Biol Trace Elem Res. 2008 Summer;123(1-3):58-65. doi: 10.1007/s12011-008-8112-0. Epub 2008 Feb 21.
Zinc, copper, and selenium statuses were reported to be linked to the development of chronic diseases, especially coronary heart disease (CHD). Metabolic syndrome, a known CHD risk factor, was found to be highly prevalent in Lebanon. Nevertheless, no data are available on the statuses of plasma zinc, copper, and selenium, especially in terms of their relation to the components of the metabolic syndrome. A sample of 398 men and women aged 18-65 years was drawn from 23 health centers across Lebanon; anthropometric measurements and biochemical analyses of fasting plasma samples were performed. Subjects were found to have normal plasma statuses of copper and selenium but were at elevated risk of zinc deficiency. Plasma selenium levels correlated positively with all the components of the metabolic syndromes, while that of copper correlated only with total, high-density lipoprotein and low-density lipoprotein cholesterol. Plasma zinc did not correlate with any of the metabolic syndrome components.
据报道,锌、铜和硒的状态与慢性疾病的发展有关,尤其是冠心病(CHD)。代谢综合征是一种已知的冠心病危险因素,在黎巴嫩被发现非常普遍。然而,目前尚无关于血浆锌、铜和硒状态的数据,特别是它们与代谢综合征各组成部分的关系。从黎巴嫩各地的23个健康中心抽取了398名年龄在18 - 65岁之间的男性和女性样本;对空腹血浆样本进行了人体测量和生化分析。研究发现,受试者的血浆铜和硒状态正常,但锌缺乏风险较高。血浆硒水平与代谢综合征的所有组成部分呈正相关,而铜水平仅与总胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇相关。血浆锌与任何代谢综合征组成部分均无相关性。