Suppr超能文献

老年患者刺激唾液中简化龋病风险测试

A simplified caries risk test in stimulated saliva from elderly patients.

作者信息

Sánchez-García Sergio, Gutiérrez-Venegas Gloria, Juárez-Cedillo Teresa, Reyes-Morales Hortensia, Solórzano-Santos Fortino, García-Peña Carmen

机构信息

Unidad de Investigación Epidemiológica y en Servicios de Salud, Area de Envejecimiento, Centro Médico Nacional Siglo XXI (CMN-SXXI), Instituto Mexicano del Seguro Social (IMSS), México City, México.

出版信息

Gerodontology. 2008 Mar;25(1):26-33. doi: 10.1111/j.1741-2358.2007.00184.x.

Abstract

OBJECTIVES

To evaluate and compare lactobacilli species (LB) and mutans streptococci (MS) caries risk identification by means of a Caries Risk Test Bacteria (CRT Bacteria test), with a conventional laboratory test (CLT), as well as their correlation with the dental caries experience [(decayed-missing-filled teeth (DMFT index)] in subjects 60 years of age and older.

DESIGN

Cross-sectional study.

SETTING

Epidemiologic and Health Service Research Unit, Aging Area. XXI Century National Medical Center; Mexican Institute of Social Security (IMSS).

SUBJECTS

A total of 696 elderly subjects residing in southwestern Mexico City.

METHODS

The DMFT index was determined in 696 subjects and saliva collected by stimulation. This was processed with a CRT Bacteria test and a CLT (the gold standard) test. Subjects with high [> or =10(5) colony forming units (CFU)/ml] and low caries risk (<10(5) CFU/ml) were assessed.

RESULTS

The CRT Bacteria test sensitivity (Sen) and specificity (Spe) were 0.97 and 0.86 for LB, respectively, with positive and negative predictor values of 0.92 and 0.95 respectively. For MS, Sen and Spe was 0.92 and 0.90, and 0.96 and 0.81 respectively. The receiver operating characteristic area under the curve (ROC area) in LB and MS was 0.94 and 0.89, respectively; thus, a correlation existed between the caries experience and the LB and MS caries risk, similar to that present with the CLT test.

CONCLUSION

The CRT Bacteria test shows similar results to those of the CLT test in subjects 60 years of age and over.

摘要

目的

通过龋病风险细菌检测(CRT细菌检测)评估并比较乳酸杆菌属(LB)和变形链球菌(MS)的龋病风险识别情况,同时与传统实验室检测(CLT)进行比较,并研究它们与60岁及以上受试者的龋病患病经历[(龋失补牙数(DMFT指数))]之间的相关性。

设计

横断面研究。

地点

二十一世纪国家医学中心老龄化领域的流行病学与卫生服务研究室;墨西哥社会保障局(IMSS)。

研究对象

共696名居住在墨西哥城西南部的老年受试者。

方法

测定696名受试者的DMFT指数,并通过刺激采集唾液。唾液样本分别采用CRT细菌检测和CLT(金标准)检测进行处理。对龋病风险高[≥10⁵菌落形成单位(CFU)/毫升]和低(<10⁵CFU/毫升)的受试者进行评估。

结果

CRT细菌检测中,LB的敏感度(Sen)和特异度(Spe)分别为0.97和0.86,阳性预测值和阴性预测值分别为0.92和0.95。对于MS,Sen和Spe分别为0.92和0.90,以及0.96和0.81。LB和MS的曲线下面积(ROC面积)分别为0.94和0.89;因此,龋病患病经历与LB和MS的龋病风险之间存在相关性,与CLT检测结果相似。

结论

CRT细菌检测在60岁及以上受试者中的结果与CLT检测相似。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验