Zierhut M, Klein R, Berg P, Thiel H J
Abt. I. Universitäts-Augenklinik Tübingen.
Klin Monbl Augenheilkd. 1991 Mar;198(3):165-73. doi: 10.1055/s-2008-1045946.
Autoimmune diseases are the result of a false recognition by the immune system of the own tissue as foreign. Suppressor cells serve to inhibit these mechanisms, however, their influence can be bypassed by other cells. Many antigen structures have been isolated in the uvea. With them it is possible to induce a model of autoimmune uveitis. The diagnostic value of eye specific and non-specific autoantibodies in uveitis patients was studied. In this report are show indications of autoimmune phenomena in the following diseases: sympathetic uveitis, Behçet's disease, Vogt-Koyanagi-Harada syndrome and birdshot retinopathy.
自身免疫性疾病是免疫系统将自身组织错误识别为外来组织的结果。抑制细胞有助于抑制这些机制，然而，其他细胞可以绕过它们的影响。在葡萄膜中已分离出许多抗原结构。利用它们可以诱导出自身免疫性葡萄膜炎模型。研究了葡萄膜炎患者眼部特异性和非特异性自身抗体的诊断价值。本报告显示了以下疾病中自身免疫现象的迹象：交感性眼炎、白塞病、小柳原田综合征和鸟枪弹样视网膜病变。
