靶向细菌的Z环。
Targeting the bacterial Z-ring.
作者信息
Vollmer Waldemar
机构信息
Institute for Cell and Molecular Biosciences, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.
出版信息
Chem Biol. 2008 Feb;15(2):93-4. doi: 10.1016/j.chembiol.2008.02.001.
Abstract
FtsZ is a prokaryotic homolog of eukaryotic tubulin and forms the essential bacterial cell division ring (Z-ring). A new study in this issue of Chemistry & Biology, Läppchen et al., provides further evidence that differences in nucleotide-binding properties of FtsZ and tubulin can be exploited to specifically target the bacterial Z-ring.
摘要
FtsZ是真核微管蛋白在原核生物中的同源物，可形成细菌必需的细胞分裂环（Z环）。本期《化学生物学》上发表的一项新研究，由拉普申等人进行，进一步证明了可以利用FtsZ和微管蛋白在核苷酸结合特性上的差异，来特异性靶向细菌的Z环。
Zotero 插件