Fontes D, Fournet J C, Lortat-Jacob A, Benoit J
Service de Chirurgie Orthopédique et Traumatologique, Hôpital A. Paré, Boulogne.
Rev Chir Orthop Reparatrice Appar Mot. 1991;77(1):1-5.
The experimentation was based on the analysis of revascularization phenomenons and reossification of cross allografts of Wistar rat femoral diaphysis firstly canalized with an epigastric subcutaneous intramedullar autogenous flap. An endosteal revascularization has been observed in addition to the periosteal one which is usually the sole characteristic of classic allografts. The bone transplant, quickly vascularized after a short period of creeping substitution, had normal histomechanical properties which were never observed without the addition of a vascular pedicule. The use of such cortical allografts seems to be useful in human surgery.
该实验首先基于对用腹壁皮下髓内自体皮瓣先行髓管化的Wistar大鼠股骨干交叉异体移植的血管再生现象和再骨化的分析。除了骨膜血管再生(这通常是经典异体移植的唯一特征)外,还观察到了骨内膜血管再生。骨移植在经过短时间的潜行替代后迅速血管化,具有正常的组织力学特性,而在未添加血管蒂的情况下从未观察到这种特性。这种皮质异体移植的应用在人类手术中似乎是有用的。