Válka J, Smahel J, Novák O
Klinika plastické a estetické chirurgie, Brno.
Acta Chir Orthop Traumatol Cech. 1993;60(3):167-70.
For investigation of revascularization of free autogenous bone grafts by implantation of blood vessels the authors used rats as experimental material. The arteries or bundles of arteries were implanted into the spongiosa of the free bone transplant--a tall vertebra. It was revealed that capillary proliferation which promotes revascularization of the graft started in the adventitia of the implanted artery. Therefore it is not necessary to severe the artery, as recommended in methods used in previous studies. Revascularization occurs even when the implanted artery retains its original function. Implantation of blood vessels does not prevent extensive necrosis of the graft but indicates osteogenesis which results in substitution of the necrotic tissue.
为了通过植入血管来研究游离自体骨移植的血管再生情况,作者使用大鼠作为实验材料。将动脉或动脉束植入游离骨移植体——一个高位椎体的海绵质中。结果发现,促进移植体血管再生的毛细血管增殖始于植入动脉的外膜。因此,无需像以往研究方法中所建议的那样切断动脉。即使植入的动脉保留其原有功能,血管再生仍会发生。植入血管并不能防止移植体广泛坏死,但表明有骨生成,这会导致坏死组织被替代。