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斜切向光子束的表面剂量测定:一项蒙特卡罗模拟研究。

Surface dosimetry for oblique tangential photon beams: a Monte Carlo simulation study.

作者信息

Chow James C L, Grigorov Grigor N

机构信息

Radiation Medicine Program, Princess Margaret Hospital and Department of Radiation Oncology, University of Toronto, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada.

出版信息

Med Phys. 2008 Jan;35(1):70-6. doi: 10.1118/1.2818956.

Abstract

The effect of beam obliquity on the surface relative dose profiles for the tangential photon beams was studied. The 6 and 15 MV photon beams with 4 x 4 and 10 x 10 cm2 field sizes produced by a Varian 21 EX linear accelerator were used. Phase-space models of the photon beams were created using Monte Carlo simulations based on the EGSnrc code, and were verified using film measurements. The relative dose profiles in the phantom skin, at 2 mm depth from the surface of the half-phantom geometry, or HPG, were calculated for increasing gantry angles from 270 to 280 deg clockwise. Relative dose profiles of a full phantom enclosing the whole tangential beam (full phantom geometry, or FPG) were also calculated using Monte Carlo simulation as a control for comparison. The results showed that, although the relative dose profiles in the phantom skin did not change significantly with an oblique beam using a FPG, the surface relative depth dose was increased for the HPG. In the HPG, with 6 MV photon beams and field size = 10 x 10 cm2, when the beam angle, starting from 270 deg, was increased from 1 to 3 deg, the relative depth doses in the phantom skin were increased from 68% to 79% at 10 cm depth. This increase in dose was slightly larger than the dose from 15 MV photon beams with the same field size and beam angles, where the relative depth doses in phantom skin were increased from 81% to 87% at 10 cm depth. A parameter called the percent depth dose (PDD) ratio, defined as the relative depth dose from the HPG to the relative depth dose from the FPG at a given depth along the phantom skin, was used to evaluate the effect of the phantom-air interface. It is found that the PDD ratio increased significantly when the beam angle was changed from zero to 1-3 degrees. Moreover, the PDD ratio, for a given field size, experienced a greater increase for 6 MV than for 15 MV. For the same photon beam energy, the PDD ratio increased more with a 4 x 4 cm2 field compared to 10 x 10 cm2. The results in this study will be useful for physicists and dosimetrists to predict the surface relative dose variations when using clinical tangential-like photon beams in radiation therapy.

摘要

研究了射束倾斜度对切线光子束表面相对剂量分布的影响。使用瓦里安21EX直线加速器产生的6和15MV光子束,其射野尺寸分别为4×4和10×10cm²。基于EGSnrc代码,通过蒙特卡罗模拟创建光子束的相空间模型,并使用胶片测量进行验证。对于顺时针从270度到280度增加的机架角度,计算了半体模几何结构(HPG)表面下2mm深度处体模皮肤中的相对剂量分布。还使用蒙特卡罗模拟计算了包围整个切线束的全体模(全体模几何结构,或FPG)的相对剂量分布,作为对照进行比较。结果表明,尽管使用FPG时,倾斜射束下体模皮肤中的相对剂量分布没有显著变化,但HPG的表面相对深度剂量增加。在HPG中,对于6MV光子束和射野尺寸 = 10×10cm²,当射束角度从270度开始增加1至3度时,在10cm深度处体模皮肤中的相对深度剂量从68%增加到79%。这种剂量增加略大于相同射野尺寸和射束角度的15MV光子束的剂量增加,在15MV光子束中,10cm深度处体模皮肤中的相对深度剂量从81%增加到87%。使用一个称为百分深度剂量(PDD)比的参数来评估体模 - 空气界面的影响,该参数定义为沿体模皮肤给定深度处HPG的相对深度剂量与FPG的相对深度剂量之比。发现当射束角度从零度变为1 - 3度时,PDD比显著增加。此外,对于给定的射野尺寸,6MV的PDD比增加幅度大于15MV。对于相同的光子束能量,与10×10cm²相比,4×4cm²射野的PDD比增加更多。本研究结果将有助于物理学家和剂量师预测在放射治疗中使用临床切线样光子束时表面相对剂量的变化。

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