King Van L, Burke Christopher, Stoller Kenneth B, Neufeld Karin J, Peirce Jessica, Kolodner Ken, Kidorf Michael, Brooner Robert K
The Johns Hopkins University School of Medicine and Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, USA.
J Subst Abuse Treat. 2008 Oct;35(3):312-21. doi: 10.1016/j.jsat.2007.12.002. Epub 2008 Feb 21.
Methadone medical maintenance (MMM) is an effective intervention that minimizes the demands of opioid agonist treatment without compromising good treatment response. Despite the benefits of MMM to both patients and treatment programs, little information is available to help community-based programs implement MMM and select patients who might benefit from this intervention. This study evaluates the impact of a seven-session seminar presentation combined with optional on-site consultation on subsequent changes in clinical programming and on the opinions of community-based treatment staff (n = 96) in five methadone maintenance treatment clinics regarding both the adoption of an MMM protocol and the use of an adaptive stepped care model to deliver it. The presentations were developed based on results from a randomized clinical trial (King, V. L., Kidorf, M. S., Stoller, K. B., Schwartz, R., Kolodner, K., Brooner, R. K. (2006) A 12-month controlled trial of methadone medical maintenance integrated into an adaptive treatment model. Journal of Substance Abuse Treatment 31, 385-393.) together with other studies of MMM to help program staff (a) understand the risks and benefits of MMM, (b) develop criteria to choose who may benefit from MMM, and (c) implement an adaptive stepped care delivery system that includes MMM as the least restrictive level of care. A survey of clinic staff opinion about MMM and stepped care was administered at baseline and at five other points over the course of the 1-year project. Overall, the presentations were rated highly favorable for content and presentation (3.3 on a 4-point scale). At the 12-month follow-up, staff were more likely to believe that MMM facilitates patient participation in community-based rehabilitation oriented activities (p = .026) and that MMM patients receive adequate counseling services (p = .025) and were more likely to support treatment that matches patients who are stable with minimal intensities of care (p = .041). One clinic modified its routine care to an adaptive stepped care model in response to the presentations, and 3 of the 5 clinics used MMM levels of treatment intensity at the end of the project. The results suggest that seminar presentations combined with on-site consultation may be a beneficial mechanism for helping staff at community-based programs learn about and adopt effective interventions developed and tested using rigorous research designs.
美沙酮药物维持治疗(MMM)是一种有效的干预措施,它能在不影响良好治疗效果的情况下,将阿片类激动剂治疗的需求降至最低。尽管MMM对患者和治疗项目都有好处,但几乎没有信息可帮助社区项目实施MMM并选择可能从该干预措施中受益的患者。本研究评估了一场为期七节的研讨会报告以及可选的现场咨询,对五个美沙酮维持治疗诊所的临床项目后续变化以及社区治疗工作人员(n = 96)对于采用MMM方案和使用适应性阶梯式照护模式来实施该方案的看法的影响。这些报告是基于一项随机临床试验的结果(金,V. L.,基多夫,M. S.,斯托勒,K. B.,施瓦茨,R.,科洛德纳,K.,布鲁纳,R. K.(2006年)将美沙酮药物维持治疗纳入适应性治疗模式的12个月对照试验。《药物滥用治疗杂志》31,385 - 393。)以及其他关于MMM的研究编写而成,以帮助项目工作人员(a)了解MMM的风险和益处,(b)制定选择可能从MMM中受益的人的标准,以及(c)实施一种适应性阶梯式照护提供系统,该系统将MMM作为限制最少的照护级别。在这个为期1年的项目过程中,在基线以及其他五个时间点对诊所工作人员关于MMM和阶梯式照护的意见进行了调查。总体而言,这些报告在内容和展示方面得到了高度好评(4分制下为3.3分)。在12个月的随访中,工作人员更有可能认为MMM有助于患者参与以社区为基础的康复导向活动(p = 0.026),并且MMM患者能获得足够的咨询服务(p = 0.025),并且更有可能支持为稳定且护理强度最小的患者匹配的治疗(p = 0.041)。一家诊所根据这些报告将其常规护理改为适应性阶梯式照护模式,并且在项目结束时,5家诊所中有3家使用了MMM治疗强度级别。结果表明,研讨会报告与现场咨询相结合可能是一种有益的机制,有助于社区项目的工作人员了解并采用通过严谨研究设计开发和测试的有效干预措施。