Eisner Brian H, Shaikh Mehrine, Uppot Raul N, Sahani Dushyant V, Dretler Stephen P
Kidney Stone Center, Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
J Urol. 2008 Apr;179(4):1445-8. doi: 10.1016/j.juro.2007.11.074. Epub 2008 Mar 4.
Noncontrast computerized tomography has replaced excretory urography as the first line diagnostic tool for evaluating nephrolithiasis at many centers. We evaluated the ability of noncontrast computerized tomography to detect ureteral duplication to determine how frequently these anomalies are under diagnosed.
Computerized tomography images of 14 patients with known ureteral duplication who had previously undergone noncontrast and contrast enhanced computerized tomography and 5 control patients with normal ureteral anatomy were interpreted by 2 blinded radiologists who specialize in genitourinary imaging.
The sensitivity of axial computerized tomography with contrast material, axial computerized tomography without contrast material and coronal computerized tomography without contrast material was 96%, 59% and 65%, respectively. The negative predictive value of axial computerized tomography with contrast material, axial computerized tomography without contrast material and coronal computerized tomography without contrast material was 95%, 65% and 67%, respectively. The accuracy of axial computerized tomography with contrast medium was significantly higher than that of noncontrast axial or noncontrast coronal computerized tomography (each p <0.01).
Duplicated ureters, which represent a challenge to the endourologist, are under diagnosed on noncontrast computerized tomography. Urologists and radiologists should be aware of this limitation and contrast studies should be done when anatomical anomalies are suspected.
