携带CT-26癌细胞的Balb/c小鼠肠道内分泌细胞减少。
Decrease in intestinal endocrine cells in Balb/c mice with CT-26 carcinoma cells.
作者信息
Cho Kwang-Ho, Lee Hyeung-Sik, Ku Sae-Kwang
机构信息
Department of Radiological Science, College of Health Science, Catholic University of Daegu, Daegu 712-702, Korea.
出版信息
J Vet Sci. 2008 Mar;9(1):9-14. doi: 10.4142/jvs.2008.9.1.9.
Abstract
The density of intestinal endocrine cells, in Balb/c mice with colon 26 (CT-26) carcinoma cells, were examined immunohistochemically at 28 days after implantation. After CT-26 cell administration there was a significant decrease in most of the intestinal endocrine cells (p < 0.01) compared with the control group. The significant quantitative changes in the intestinal endocrine cell density might contribute to the development of the gastrointestinal symptoms commonly encountered in cancer patients.
摘要
在植入结肠26（CT - 26）癌细胞的Balb/c小鼠中，于植入后28天通过免疫组织化学方法检测肠道内分泌细胞的密度。与对照组相比，给予CT - 26细胞后，大多数肠道内分泌细胞显著减少（p < 0.01）。肠道内分泌细胞密度的显著定量变化可能促成癌症患者常见的胃肠道症状的发展。
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本文引用的文献
1
Changes of the intestinal endocrine cells in the C57BL/6 mouse after implantation of murine lung carcinoma (3LL): an immunohistochemical quantitative study.
World J Gastroenterol. 2005 Sep 21;11(35):5460-7. doi: 10.3748/wjg.v11.i35.5460.
2
An immunohistochemical study of gastrointestinal endocrine cells in the BALB/c mouse.
Anat Histol Embryol. 2004 Feb;33(1):42-8. doi: 10.1111/j.1439-0264.2004.00508.x.
3
An immunohistochemical study of the gastrointestinal endocrine cells in the C57BL/6 mice.
Anat Histol Embryol. 2003 Feb;32(1):21-8. doi: 10.1046/j.1439-0264.2003.00433.x.
4
Gastrointestinal symptoms among inpatients with advanced cancer.
Am J Hosp Palliat Care. 2002 Sep-Oct;19(5):351-5. doi: 10.1177/104990910201900513.
5
Abnormal gastrointestinal endocrine cells in patients with diabetes type 1: relationship to gastric emptying and myoelectrical activity.
Scand J Gastroenterol. 2001 Nov;36(11):1162-9. doi: 10.1080/00365520152584789.
6
Immunohistochemical localization of chromogranin A and B in the endocrine cells of the alimentary tract of the green frog, Rana esculenta.
Cell Tissue Res. 1994 Aug;277(2):341-9. doi: 10.1007/BF00327782.
7
Immunocytochemical distribution of endocrine cells in the gastrointestinal tract of the horse.
Equine Vet J. 1984 Mar;16(2):103-7. doi: 10.1111/j.2042-3306.1984.tb01870.x.
8
Selective localization of the parathyroid secretory protein-I/adrenal medulla chromogranin A protein family in a wide variety of endocrine cells of the rat.
Endocrinology. 1984 Jun;114(6):1963-74. doi: 10.1210/endo-114-6-1963.
9
A quantitative study of enteric endocrine cells in celiac sprue.
J Pediatr Gastroenterol Nutr. 1984 Nov;3(5):665-71. doi: 10.1097/00005176-198411000-00004.
10
Gut endocrine cells in rat intestinal-tract carcinoma induced by 1,2-dimethylhydrazine.
J Cancer Res Clin Oncol. 1983;105(3):221-30. doi: 10.1007/BF00395749.
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