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记忆构建与意义获取的初级干预(PIMSMA):对急诊室中自杀式爆炸袭击受伤幸存者进行心理健康急救干预的研究

Primary intervention for memory structuring and meaning acquisition (PIMSMA): study of a mental health first-aid intervention in the ED with injured survivors of suicide bombing attacks.

作者信息

Schreiber Shaul, Dolberg Ornah T, Barkai Gabriel, Peles Einat, Leor Agnes, Rapoport Elena, Heinik Jeremia, Bloch Miki

机构信息

Department of Psychiatry, Tel Aviv Sourasky Medical Center, Israel.

出版信息

Am J Disaster Med. 2007 Nov-Dec;2(6):307-20.

Abstract

OBJECTIVE

To assess the impact of a structured intervention, the "primary intervention for memory structuring and meaning acquisition" (PIMSMA) performed randomly in the emergency department with survivors of suicide bombing attacks, on their medium-term mental health outcome.

DESIGN

Follow up and assessment 3-9 months postinjury, and 24 months thereafter.

SETTING

A tertiary referral general hospital in Tel Aviv, Israel.

PARTICIPANTS

Injured survivors of 9 suicide bombing and suicide shooting, men and women aged 16-72 at the time of the incident.

MAIN OUTCOME MEASURES

Diagnosis of posttraumatic stress disorder (PTSD) was made using the Hebrew validated version of the DSM-IV SCID-PTSD rating scale. Other psychiatric symptoms were assessed using the following rating scales: impact of event scale (IES), Hamilton rating scale for depression (HAM-D) and for anxiety (HAM-A), and the Pittsburgh sleep quality index (PSQI). Effects of PIMSMA and PTSD level of psychological distress were analyzed using ANOVA and for change over time for continuous variables repeated measured multivariate analyses was performed, and for categorical variables nonparametric-related sample McNemar. Logistic regression for variable associated with PTSD was performed.

RESULTS

Out of 213 eligible injured survivors evacuated to our ER, 129 were retrieved 3-9 months after the incident, and 53 were available for assessment 2 years later. Multivariate analyses for being PTSD vs non-PTSD at the first evaluation, being hospitalized OR = 5.6 (95 percent CI 1.1-27.6) and treated OR = 24.5 (95 percent CI 2.8-200) were the only predictors, with no effect (p = 0.9) for PIMSMA vs other supportive intervention. Predictor for PTSD at the second evaluation were IES severity score at first evaluation OR = 1.1 (95 percent CI 1.04-1.2).

CONCLUSION

The PIMSMA approach is as good as the nonspecific supportive treatment performed routinely in the ED with all survivors of traumatic events of any origin. Further studies are needed to establish valid, evidence-based treatment approaches for the acute aftermath of exposure to severe potentially traumatic events.

摘要

目的

评估一种结构化干预措施,即“记忆构建与意义获取初级干预”(PIMSMA),在急诊科对自杀式爆炸袭击幸存者随机实施后,对其心理健康中期结果的影响。

设计

受伤后3 - 9个月进行随访和评估,此后24个月进行随访和评估。

地点

以色列特拉维夫的一家三级转诊综合医院。

参与者

9起自杀式爆炸和自杀式枪击事件的受伤幸存者,事件发生时年龄在16 - 72岁之间的男性和女性。

主要结局指标

使用经希伯来语验证的DSM-IV SCID - PTSD评定量表诊断创伤后应激障碍(PTSD)。使用以下评定量表评估其他精神症状:事件影响量表(IES)、汉密尔顿抑郁评定量表(HAM - D)和焦虑评定量表(HAM - A)以及匹兹堡睡眠质量指数(PSQI)。使用方差分析(ANOVA)分析PIMSMA和PTSD心理痛苦水平的影响,对于连续变量随时间的变化进行重复测量多元分析,对于分类变量进行非参数相关样本麦克内马尔检验。对与PTSD相关的变量进行逻辑回归分析。

结果

在被疏散到我们急诊科的213名符合条件的受伤幸存者中,事件发生后3 - 9个月找回了129名,2年后有53名可进行评估。首次评估时PTSD与非PTSD的多变量分析显示,住院比值比(OR)= 5.6(95%可信区间1.1 - 27.6)和接受治疗比值比(OR)= 24.5(95%可信区间2.8 - 200)是唯一的预测因素,PIMSMA与其他支持性干预相比无影响(p = 0.9)。第二次评估时PTSD的预测因素是首次评估时的IES严重程度评分,OR = 1.1(95%可信区间1.04 - 1.2)。

结论

PIMSMA方法与急诊科对任何来源创伤事件的所有幸存者常规进行的非特异性支持性治疗效果相当。需要进一步研究以建立针对严重潜在创伤事件暴露后急性期的有效、基于证据的治疗方法。

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