van de Nieuwenhof H P, van Ham M A P C, Lotgering F K, Massuger L F A G
Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Int J Gynecol Cancer. 2008 Nov-Dec;18(6):1381-5. doi: 10.1111/j.1525-1438.2008.01193.x. Epub 2008 Feb 19.
Women who present with cervical carcinoma during pregnancy pose for us a clinical problem. In general, three treatment options exist: (i) radical hysterectomy with termination of pregnancy, (ii) a planned delay, or (iii) chemotherapy until lung maturation has occurred, both followed by a radical hysterectomy. Vaginal radical trachelectomy is an alternative approach to preserve the pregnancy. We report on a woman with a stage IBI cervical carcinoma, diagnosed at 16 weeks of gestation treated with vaginal radical trachelectomy. At a gestational age of 36 weeks, a cesarean section was performed, followed by radical hysterectomy. Follow-up of 9 months is uneventful for both the mother and the child. The vaginal radical trachelectomy is a new approach in the treatment of cervical carcinoma during pregnancy.
孕期出现宫颈癌的女性给我们带来了一个临床问题。一般来说，有三种治疗选择：（i）根治性子宫切除术并终止妊娠，（ii）计划延迟治疗，或（iii）化疗直至肺成熟，随后均进行根治性子宫切除术。阴道根治性宫颈切除术是一种保留妊娠的替代方法。我们报告了一名患有ⅠB1期宫颈癌的女性，在妊娠16周时被诊断出来，接受了阴道根治性宫颈切除术。在孕36周时，进行了剖宫产，随后进行了根治性子宫切除术。母亲和孩子的9个月随访均无异常。阴道根治性宫颈切除术是孕期宫颈癌治疗的一种新方法。
