Gorbacheva O N, Zharova E A, Masenko V P, Nasonov E L, Samoriadova O S, Karpov Iu A
Ter Arkh. 1991;63(4):48-50.
A study was made of the concentration of endothelin (ET) in the plasma of patients suffering from arterial hypertension (AH), heart failure (HF) and in that of healthy volunteers. The concentration of ET in the normal subjects was within 4.0-8.6 pg/ml, in the patients with AH, it varied from 5.7 to 64.5 pg/ml, and in the patients suffering from HF, from 8.8 to 94.0 pg/ml. A subgroup of patients with essential hypertension, stage II B, showed a tendency towards a rise of the ET concentration in response to orthostatic load that was associated with an increase of the concentration of angiotensin-2.
对患有动脉高血压（AH）、心力衰竭（HF）的患者以及健康志愿者血浆中的内皮素（ET）浓度进行了研究。正常受试者体内ET浓度在4.0 - 8.6 pg/ml之间，AH患者体内ET浓度在5.7至64.5 pg/ml之间，HF患者体内ET浓度在8.8至94.0 pg/ml之间。患有原发性高血压II B期的患者亚组显示，ET浓度有因体位负荷而升高的趋势，这与血管紧张素-2浓度增加有关。
