Jirásková Nada, Kadlecová Jana, Rozsíval Pavel, Nekolová Jana, Pozlerova Jana, Dúbravská Zlatica
Department of Ophthalmology, University Hospital, Hradec Králové, Czech Republic.
J Cataract Refract Surg. 2008 Mar;34(3):377-82. doi: 10.1016/j.jcrs.2007.10.033.
To compare the extent of corneal endothelial cell loss and pachymetry changes in 2 age-based groups of patients who had cataract removal by AquaLase (Alcon) phacoemulsification in 1 eye and NeoSoniX (Alcon) phacoemulsification in the contralateral eye.
Department of Ophthalmology, University Hospital, Hradec Králové, Czech Republic.
This prospective clinical study comprised 28 patients younger than 80 years (Group A) and 28 patients 80 years or older (Group B) with bilateral cataract having lens removal using AquaLase in the right eye and NeoSoniX in the left eye. The nuclei were graded clinically on the basis of hardness. The endothelial cell count (ECC), pachymetry, and best corrected visual acuity (BCVA) were evaluated preoperatively and postoperatively. The mean ECC and pachymetry values (+/-SD) were calculated in each group, with differences between right and left eyes analyzed using the paired t test.
In Group A, the differences in the postoperative changes in ECC and pachymetry between AquaLase and NeoSoniX were not statistically significant. In Group B, there were statistically significant differences in postoperative changes in ECC and pachymetry, with the results better in the AquaLase eyes. The BCVA immediately after surgery was better than preoperatively in all eyes.
The results suggest that AquaLase cataract extraction is safe for the endothelium, even in older patients with harder cataracts and a lower ECC count preoperatively.
比较两组基于年龄的患者，一组患者一只眼睛采用AquaLase（爱尔康）超声乳化技术摘除白内障，对侧眼睛采用NeoSoniX（爱尔康）超声乳化技术，观察其角膜内皮细胞丢失程度和角膜厚度变化。
捷克共和国赫拉德茨克拉洛韦大学医院眼科。
这项前瞻性临床研究纳入了28例80岁以下患者（A组）和28例80岁及以上患者（B组），均为双眼白内障患者，右眼采用AquaLase超声乳化技术摘除晶状体，左眼采用NeoSoniX超声乳化技术。根据硬度对晶状体核进行临床分级。术前和术后评估内皮细胞计数（ECC）、角膜厚度和最佳矫正视力（BCVA）。计算每组的平均ECC和角膜厚度值（±标准差），使用配对t检验分析左右眼之间的差异。
在A组中，AquaLase和NeoSoniX术后ECC和角膜厚度变化的差异无统计学意义。在B组中，术后ECC和角膜厚度变化有统计学意义，AquaLase手术眼的结果更好。所有眼睛术后即时BCVA均优于术前。
结果表明，即使对于术前白内障较硬且ECC计数较低的老年患者，AquaLase白内障摘除术对内皮也是安全的。
