Verrier Paul J, Bird David, Burla Bo, Dassa Elie, Forestier Cyrille, Geisler Markus, Klein Markus, Kolukisaoglu Uner, Lee Youngsook, Martinoia Enrico, Murphy Angus, Rea Philip A, Samuels Lacey, Schulz Burkhard, Spalding Edgar J, Yazaki Kazufumi, Theodoulou Frederica L
Biomathematics and Bioinformatics Department, Rothamsted Research, Harpenden, AL5 2JQ, UK.
Trends Plant Sci. 2008 Apr;13(4):151-9. doi: 10.1016/j.tplants.2008.02.001. Epub 2008 Mar 4.
The ABC superfamily comprises both membrane-bound transporters and soluble proteins involved in a broad range of processes, many of which are of considerable agricultural, biotechnological and medical potential. Completion of the Arabidopsis and rice genome sequences has revealed a particularly large and diverse complement of plant ABC proteins in comparison with other organisms. Forward and reverse genetics, together with heterologous expression, have uncovered many novel roles for plant ABC proteins, but this progress has been accompanied by a confusing proliferation of names for plant ABC genes and their products. A consolidated nomenclature will provide much-needed clarity and a framework for future research.
ABC超家族既包括膜结合转运蛋白,也包括参与广泛过程的可溶性蛋白质,其中许多过程具有相当大的农业、生物技术和医学潜力。与其他生物相比,拟南芥和水稻基因组序列的完成揭示了植物ABC蛋白特别庞大且多样的补充。正向和反向遗传学,以及异源表达,已经揭示了植物ABC蛋白的许多新作用,但这一进展伴随着植物ABC基因及其产物名称的混乱增加。一个统一的命名法将为未来的研究提供急需的清晰度和框架。