Frosch Dominick L, Bhatnagar Vibha, Tally Steven, Hamori Charles J, Kaplan Robert M
Division of General Internal Medicine and Health Services Research, Department of Medicine, University of California Los Angeles, Los Angeles, CA 90024, USA.
Arch Intern Med. 2008 Feb 25;168(4):363-9. doi: 10.1001/archinternmed.2007.111.
We conducted a randomized controlled trial to evaluate the effects of patient decision support Web sites on decision quality for men considering prostate cancer screening.
Men older than 50 years (N = 611) were randomly assigned to 1 of 4 Internet conditions: traditional didactic decision aid providing information about prostate-specific antigen (PSA) screening options and outcomes; chronic disease trajectory model for prostate cancer followed by a time-trade-off exercise; both the didactic decision aid and the chronic disease trajectory model; or links to public prostate cancer-specific Web sites from credible sources (control condition). Participants completed questionnaires at baseline and after their physical examination. Primary outcome measures were PSA test choice, prostate cancer treatment preferences, knowledge and concern about prostate cancer, and decisional conflict.
Participants assigned to view public Web sites were less likely to review information (116 participants [76.8%] reviewed) than those assigned to experimental groups (399 [86.7%] reviewed; P = .004). Greater reductions in PSA screening from pretest to posttest were observed among participants assigned to the traditional decision aid (-9.1%) or chronic disease trajectory model (-8.7%), compared with participants assigned to the combination (-5.3%) or control (-3.3%) groups (P = .047). Preferences for watchful waiting increased significantly in all 4 groups (baseline, 219 [35.8%]; follow-up, 303 [66.2%]; P < .001). Knowledge scores were lowest for those assigned to public Web sites (mean [SD] score, 7.49 [0.19] of questions correct) and highest for the traditional decision aid (8.65 [0.18] of questions correct; P = .005).
Public Web sites about prostate cancer provide less effective decision support than a specially designed Internet decision aid.
我们进行了一项随机对照试验,以评估患者决策支持网站对考虑前列腺癌筛查的男性决策质量的影响。
年龄超过50岁的男性(N = 611)被随机分配到4种互联网条件之一:提供有关前列腺特异性抗原(PSA)筛查选项和结果信息的传统说教式决策辅助工具;前列腺癌慢性病轨迹模型,随后进行时间权衡练习;说教式决策辅助工具和慢性病轨迹模型两者;或来自可靠来源的公共前列腺癌特定网站链接(对照条件)。参与者在基线时和体检后完成问卷调查。主要结局指标为PSA检测选择、前列腺癌治疗偏好、对前列腺癌的知识和关注以及决策冲突。
与被分配到实验组的参与者(399人[86.7%]进行了查看;P = 0.004)相比,被分配查看公共网站的参与者查看信息的可能性较小(116名参与者[76.8%]进行了查看)。与被分配到联合组(-5.3%)或对照组(-3.3%)的参与者相比,被分配到传统决策辅助工具组(-9.1%)或慢性病轨迹模型组(-8.7%)的参与者从测试前到测试后PSA筛查的减少幅度更大(P = 0.047)。在所有4组中,观察等待的偏好均显著增加(基线时,219人[35.8%];随访时,303人[66.2%];P < 0.001)。被分配到公共网站的参与者知识得分最低(正确回答问题的平均[标准差]得分,7.49[0.19]),而传统决策辅助工具组得分最高(正确回答问题的8.65[0.18];P = 0.005)。
关于前列腺癌的公共网站提供的决策支持比专门设计的互联网决策辅助工具效果更差。