School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Mitato-ku, Tokyo 108-8641, Japan.
J Clin Biochem Nutr. 2007 Nov;41(3):154-9. doi: 10.3164/jcbn.2007021.
Lansoprazole uptake sites by two kinds of autoradiographic procedures were compared with recent literature. The uptake sites have been seen in the Helicobacter pylori, colonic epithelial cells, inflammatory cells, peripheral autonomic nerves and enterochromaffinlike cells as well as gastric parietal cells. Each uptake sites corresponded to the reported localization of P-type ATPase or acidic compartment.
采用两种放射性自显影技术对兰索拉唑摄取部位进行了比较,并与近期文献进行了比较。摄取部位见于幽门螺杆菌、结肠上皮细胞、炎症细胞、周围自主神经和肠嗜铬样细胞以及胃壁细胞。每个摄取部位都与报道的 P 型 ATP 酶或酸性区室的定位相对应。