Shimokawa N, Komura S, Andelman D
Department of Chemistry, Graduate School of Science and Engineering, Tokyo Metropolitan University, Tokyo, Japan.
Eur Phys J E Soft Matter. 2008 May-Jun;26(1-2):197-204. doi: 10.1140/epje/i2007-10258-4. Epub 2008 Feb 26.
We propose a model describing liquid-solid phase coexistence in mixed lipid membranes by including explicitly the occurrence of a rippled phase. For a single component membrane, we employ a previous model in which the membrane thickness is used as an order parameter. As function of temperature, this model properly accounts for the phase behavior of the three possible membrane phases: solid, liquid and the rippled phase. Our primary aim is to explore extensions of this model to binary lipid mixtures by considering the composition dependence of important model parameters. The obtained phase diagrams show various liquid, solid and rippled phase coexistence regions, and are in quantitative agreement with the experimental ones for some specific lipid mixtures.
我们提出了一个模型，通过明确包含波纹相的出现来描述混合脂质膜中的液-固相变共存。对于单组分膜，我们采用了一个先前的模型，其中膜厚度用作序参量。作为温度的函数，该模型恰当地描述了三种可能的膜相（固态、液态和波纹相）的相行为。我们的主要目标是通过考虑重要模型参数的组成依赖性，将该模型扩展到二元脂质混合物。所得到的相图显示了各种液、固和波纹相共存区域，并且在定量上与某些特定脂质混合物的实验结果一致。
