Koutsouraki Ephrosyni, Timplalexi Georgia, Papadopoulou Zoe, Costa Vasiliki, Baloyannis Stavros
1st Department of Neurology, School of Medicine, Aristotelian University, Thessaloniki, Greece.
Int J Neurosci. 2008 Mar;118(3):343-8. doi: 10.1080/00207450601050261.
This article describes a very rare case of a double cortex syndrome in a man aged 32 years old who started from the age of 14 years having seizures and many other epileptic manifestations that continue to the present age, being always intractable to various therapeutic regimes. The neuroimaging revealed cortical ectopias in the cingulum, the visual cortex, in the middle part of the superior temporal gyrus, in the frontal pole as well as in the middle area of precentral gyrus. This article attempts to underline the behavioral disturbances, the learning difficulties, the psychological fluctuations, and the multitude of the seizures that have been released during the clinical course of the patient. The article attempts to correlate the clinical phenomena of the patient and the resistance to therapeutical interventions with the morphological changes as they have been visualized by the neuroimaging techniques, reviewing in addition relevant cases from the literature.
本文描述了一例极为罕见的双皮质综合征病例，患者为一名32岁男性，自14岁起开始出现癫痫发作及许多其他癫痫表现，至今仍持续存在，对各种治疗方案均难以控制。神经影像学检查显示，扣带回、视觉皮质、颞上回中部、额极以及中央前回中部存在皮质异位。本文试图强调患者临床过程中出现的行为障碍、学习困难、心理波动以及大量癫痫发作。此外，本文还回顾了文献中的相关病例，试图将患者的临床现象、对治疗干预的抵抗与神经影像学技术所显示的形态学变化联系起来。
