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保罗·埃尔利希:1908年诺贝尔生理学或医学奖。

Paul Ehrlich: the Nobel Prize in physiology or medicine 1908.

作者信息

Piro Anna, Tagarelli Antonio, Tagarelli Giuseppe, Lagonia Paolo, Quattrone Aldo

机构信息

Istituto di Scienze Neurologiche-CNR, Mangone, Cosenza, Italy.

出版信息

Int Rev Immunol. 2008 Jan-Apr;27(1-2):1-17. doi: 10.1080/08830180701848995.

Abstract

We wish to commemorate Paul Ehrlich on the centennial of his being awarded the Nobel Prize in Physiology or Medicine in 1908. His studies are now considered as milestones in immunology: the morphology of leukocytes; his side-chain theory where he defined the cellular receptor for first time; and his clarification of the difference between serum therapy and chemotherapy. Ehrlich also invented the first chemotherapeutic drug: compound 606, or Salvarsan. We have used some original documents from the Royal Society of London, where Ehrlich was a fellow, and from Leipzig University, where he took a degree in medicine.

摘要

我们希望纪念保罗·埃尔利希(Paul Ehrlich),2008年是他荣获诺贝尔生理学或医学奖一百周年。他的研究如今被视为免疫学的里程碑:白细胞的形态学;他首次定义细胞受体的侧链理论;以及他对血清疗法和化学疗法差异的阐明。埃尔利希还发明了第一种化疗药物:606化合物,即洒尔佛散。我们使用了来自伦敦皇家学会(埃尔利希是该学会会员)以及莱比锡大学(他在该校获得医学学位)的一些原始文献。

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