Galor Anat, Lowder Careen Y, Kaiser Peter K, Perez Victor L, Sears Jonathan E
Cole Eye Institute, The Cleveland Clinic Foundation, OH 44195, USA.
Retina. 2008 Feb;28(2):282-8. doi: 10.1097/IAE.0b013e3181237d14.
To evaluate the anatomic and visual outcomes after surgical management of chronic serous retinal detachments (SRD) associated with uveitis.
Retrospective, interventional, case study of patients with uveitis with controlled ocular inflammation who underwent drainage of a chronic SRD at the Cole Eye Institute (1998-2006). Data collected included diagnosis, ophthalmic findings, medical management, surgical technique, complications, and anatomic and visual outcomes.
Five patients with uveitis were identified who underwent surgical drainage of a SRD. Preoperative medical treatment included prednisone 1 mg/kg with various tapering regimens. The median time on oral corticosteroids preoperatively was 4 months (range 3-6 months). Four patients received further adjuvant treatment. Median time from SRD diagnosis to surgical drainage was 6 months (range 3-15 months). No patient had active intraocular inflammation preoperatively. Retinal reattachment was achieved in all patients after a median follow-up of 55 months (range 1-61 months). Four of five patients experienced improvement in visual acuity after surgical intervention.
Select patients with uveitis with a SRD whose subretinal fluid fails to resorb after medical therapy and resolution of inflammation can achieve long-term retinal reattachment by surgical management.
评估与葡萄膜炎相关的慢性浆液性视网膜脱离（SRD）手术治疗后的解剖学和视觉效果。
对在科尔眼科研究所（1998 - 2006年）接受慢性SRD引流的葡萄膜炎且眼部炎症得到控制的患者进行回顾性、干预性病例研究。收集的数据包括诊断、眼科检查结果、药物治疗、手术技术、并发症以及解剖学和视觉效果。
确定了5例接受SRD手术引流的葡萄膜炎患者。术前药物治疗包括1 mg/kg泼尼松及各种逐渐减量方案。术前口服皮质类固醇的中位时间为4个月（范围3 - 6个月）。4例患者接受了进一步的辅助治疗。从SRD诊断到手术引流的中位时间为6个月（范围3 - 15个月）。术前无患者有活动性眼内炎症。所有患者在中位随访55个月（范围1 - 61个月）后视网膜均重新附着。5例患者中有4例在手术干预后视力得到改善。
对于药物治疗及炎症消退后视网膜下液仍未吸收的葡萄膜炎合并SRD的特定患者，手术治疗可实现视网膜长期重新附着。
