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重症监护中的早期营养支持:欧洲视角

Early nutrition support in critical care: a European perspective.

作者信息

Kreymann K Georg

机构信息

Department of Intensive Care, University Medical Centre, Hamburg-Eppendorf, Germany.

出版信息

Curr Opin Clin Nutr Metab Care. 2008 Mar;11(2):156-9. doi: 10.1097/MCO.0b013e3282f44c41.

Abstract

PURPOSE OF REVIEW

Today, early nutrition support is considered standard care in most ICUs. The recommended method is the enteral route, although there is only minor evidence for this. Often inadequate delivery of energy and a cumulative energy deficit are implied. The purpose of this paper is to evaluate the indication for early enteral nutrition or immunonutrition and to discuss the application of additional parenteral nutrition.

RECENT FINDINGS

The indication for early enteral nutrition is also supported by guidelines for enteral nutrition recently published by the European Society for Clinical Nutrition and Metabolism. Some more recent results strengthen the indication for a special formula in acute respiratory distress syndrome and septic patients. A recent metaanalysis has shown that parenteral nutrition is superior to delayed enteral nutrition. Additional parenteral nutrition thus seems to be the way to avoid cumulative energy deficit associated with insufficient or no enteral nutrition.

SUMMARY

Early enteral nutrition is recommended for critically ill patients, with special formulas indicated in specific subgroups of patients. If enteral nutrition is insufficient or fails, parenteral nutrition should be instituted, respecting the often reduced demand for exogenous substrates in critically ill patients.

摘要

综述目的

如今,早期营养支持在多数重症监护病房被视为标准治疗措施。推荐的方式是肠内营养途径,尽管支持这一做法的证据较少。能量供应常常不足,且存在累积能量亏空。本文旨在评估早期肠内营养或免疫营养的适应证,并探讨补充肠外营养的应用。

最新研究成果

欧洲临床营养与代谢学会近期发布的肠内营养指南也支持早期肠内营养的适应证。一些最新研究结果强化了在急性呼吸窘迫综合征和脓毒症患者中使用特殊配方的适应证。最近一项荟萃分析表明,肠外营养优于延迟肠内营养。因此,补充肠外营养似乎是避免因肠内营养不足或未进行肠内营养而导致累积能量亏空的方法。

总结

对于危重症患者推荐早期肠内营养,特定患者亚组需使用特殊配方。如果肠内营养不足或失败,应给予肠外营养,同时要考虑到危重症患者对外源性底物的需求通常会降低。

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