de Aguilar-Nascimento José E, Kudsk Kenneth A
Department of Surgery, Federal University of Mato Grosso, Cuiaba, Brazil.
Curr Opin Clin Nutr Metab Care. 2008 May;11(3):255-60. doi: 10.1097/MCO.0b013e3282fba5c6.
Early nutrition is defined as the initiation of nutritional therapy within 48 h of either hospital admission or surgery. However, optimal timing for initiation of nutritional therapy through either enteral or parenteral routes remains poorly defined with the existing data. We reviewed the recent literature investigating the role of early enteral and parenteral nutrition in critical illness and perioperative care.
Recent studies in both trauma/surgical and nonsurgical patients support the superiority of early enteral over early parenteral nutrition. However, late commencement of enteral feeding should be avoided if the gastrointestinal tract is functional. Both prolonged hypocaloric enteral feeding and hypercaloric parenteral nutrition should be avoided, although the precise caloric target remains controversial.
Early enteral nutrition remains the first option for the critically ill patient. However, there seems to be increased favor for combined enteral-parenteral therapy in cases of sustained hypocaloric enteral nutrition. The key issue is when the dual regimen should be initiated. Although more study is required to determine the optimal timing to initiate a combined enteral-parenteral approach, enteral nutrition should be initiated early and parenteral nutrition added if caloric-protein targets cannot be achieved after a few days.
早期营养被定义为在入院或手术后48小时内开始营养治疗。然而,根据现有数据,通过肠内或肠外途径开始营养治疗的最佳时机仍不明确。我们回顾了近期关于早期肠内和肠外营养在危重症和围手术期护理中作用的文献。
近期在创伤/手术患者和非手术患者中的研究均支持早期肠内营养优于早期肠外营养。然而,如果胃肠道功能正常,应避免延迟开始肠内喂养。尽管确切的热量目标仍存在争议,但应避免长时间低热量肠内喂养和高热量肠外营养。
早期肠内营养仍然是危重症患者的首选。然而,在持续低热量肠内营养的情况下,肠内-肠外联合治疗似乎更受青睐。关键问题是何时开始双重治疗方案。尽管需要更多研究来确定开始肠内-肠外联合治疗的最佳时机,但应尽早开始肠内营养,如果几天后无法达到热量-蛋白质目标,则添加肠外营养。