Fotiadis E, Kenanidis E, Samoladas E, Christodoulou A, Akritopoulos P, Akritopoulou K
Orthopaedic Department, General Hospital of Veria, Veria, Greece.
Eur Spine J. 2008 May;17(5):673-8. doi: 10.1007/s00586-008-0641-x. Epub 2008 Feb 27.
The aim of this cross-sectional case-control study is the comparison of the weight and height between a group of children with Scheuermann's disease (SD) and a comparable group of healthy ones and also the correlation of them with the degree and the morphology of the kyphotic curve. Following a school-screening program of 10,057 school students, aged between 11 and 17 years old, 175 adolescents with Scheuermann's disease were diagnosed. The mean height and weight of 175 adolescents diagnosed to have SD compared with this of a group of normal children taken randomly from the group of 9,882 healthy children screened. The control group was comparable with the study group concerning age (p = 0.605) and sex. The weight, height and body mass index (BMI) were significantly lower in the healthy (control) group (p < 0.001). However, there was no correlation between weight (r = -0.019, p = 0.804), height (r = 0.053, p = 0.484) and BMI (r = -0.177, p = 0.019) with the magnitude of kyphotic curve. There was also no correlation between weight (r = -0.27, p = 0.722), height (r = -0.025, p = 0.744) and BMI (r = -0.038, p = 0.619) with Voutsinas index as well. Scheuermann's disease is probably a multifactorial skeletal deformity. Weight and height do not seem to affect the magnitude and morphology of the main kyphotic curve in SD. It seems probably that this observation is not part of the pathogenetic mechanism of SD but a result of its cascade. The increased weight and height of these patients may be the secondary result of other disturbances (i.e. hormonal), which may play more crucial role in Scheuermann's disease pathogenesis.
这项横断面病例对照研究的目的是比较一组患有休曼氏病(SD)的儿童与一组可比的健康儿童之间的体重和身高,并研究它们与后凸曲线的程度和形态之间的相关性。在对10057名年龄在11至17岁之间的在校学生进行学校筛查项目后,诊断出175名患有休曼氏病的青少年。将175名被诊断患有SD的青少年的平均身高和体重与从9882名接受筛查的健康儿童中随机抽取的一组正常儿童的平均身高和体重进行比较。对照组在年龄(p = 0.605)和性别方面与研究组具有可比性。健康(对照)组的体重、身高和体重指数(BMI)显著较低(p < 0.001)。然而,体重(r = -0.019,p = 0.804)、身高(r = 0.053,p = 0.484)和BMI(r = -0.177,p = 0.019)与后凸曲线的严重程度之间没有相关性。体重(r = -0.27,p = 0.722)、身高(r = -0.025,p = 0.744)和BMI(r = -0.038,p = 0.619)与Voutsinas指数之间也没有相关性。休曼氏病可能是一种多因素骨骼畸形。体重和身高似乎不会影响SD中主要后凸曲线的程度和形态。似乎这种观察结果可能不是SD发病机制的一部分,而是其一系列后果的结果。这些患者体重和身高的增加可能是其他干扰(如激素)的次要结果,而这些干扰可能在休曼氏病的发病机制中起更关键的作用。