Karamanidou Christina, Weinman John, Horne Rob
Centre for Behavioural Medicine, School of Pharmacy, University of London, London, UK.
Br J Health Psychol. 2008 May;13(Pt 2):205-14. doi: 10.1348/135910708X288792. Epub 2008 Feb 26.
To evaluate a psycho-educational intervention aimed to improve understanding of the need for phosphate control, provide a rationale for phosphate-binding medication (PBM) and explain its mode of action.
A controlled intervention study comparing the effect of a self-regulatory theory-based psycho-educational intervention versus standard care control on knowledge of phosphate control and beliefs about PBM.
End-stage renal disease (ESRD) patients were assigned to either an intervention group (N=19) or control group (N=20). Both groups were assessed at baseline, at 1-month post-intervention and at 4-month post-intervention. The intervention group was also assessed immediately post-intervention.
The intervention had an immediate impact post-intervention on all outcome variables examined. It was also successful in improving knowledge, treatment coherence, medication outcome efficacy beliefs, and general understanding of treatment in the intervention group in comparison to the control group, an effect which was sustained through to the second follow-up.
A simple intervention was successful in changing patients' understanding and some beliefs around treatment thought to influence adherence behaviour. Further research is needed to inform the design of a more complex intervention targeting the specific beliefs influencing behaviour in order to facilitate treatment adherence.
评估一项心理教育干预措施,旨在提高对磷酸盐控制必要性的理解,为磷酸盐结合药物(PBM)提供理论依据,并解释其作用方式。
一项对照干预研究,比较基于自我调节理论的心理教育干预与标准护理对照对磷酸盐控制知识和对PBM信念的影响。
将终末期肾病(ESRD)患者分为干预组(N = 19)或对照组(N = 20)。两组在基线、干预后1个月和干预后4个月进行评估。干预组在干预后也立即进行评估。
干预在干预后对所有检查的结果变量都有即时影响。与对照组相比,干预组在改善知识、治疗连贯性、药物疗效信念以及对治疗的总体理解方面也取得了成功,这种效果持续到第二次随访。
一项简单的干预成功改变了患者对治疗的理解和一些被认为会影响依从行为的信念。需要进一步研究,为设计针对影响行为的特定信念的更复杂干预措施提供依据,以促进治疗依从性。