Rasheed M U, Belay Getachew
School of Medical Laboratory Technology, Medical Faculty, Jimma University, P O B 378, Jimma, Ethiopia.
Trop Doct. 2008 Jan;38(1):34-5. doi: 10.1258/td.2007.060055.
To determine the frequency of nocardiosis in HIV-positive individuals clinically suspected of having tuberculosis (TB), 140 sputum samples were collected and processed by Gram stain, modified Ziehl-Neelsen staining and by culture on Lowenstein Jensen medium. Four (2.85%) patients were positive for nocardia by microscopy and five (3.6%) had positive culture for Nocardia asterioides. In areas where HIV-associated TB is common, some patients diagnosed as smear-negative pulmonary TB will actually have nocardiosis. Clinicians should be aware of this entity in HIV/immunocompromised patients with respiratory infections who fail to respond to antituberculous treatment.
为确定临床疑似患有结核病（TB）的HIV阳性个体中诺卡菌病的发生率，收集了140份痰标本，并通过革兰氏染色、改良齐-尼氏染色以及在罗-琴培养基上培养进行处理。4例（2.85%）患者经显微镜检查诺卡菌呈阳性，5例（3.6%）星形诺卡菌培养呈阳性。在HIV相关结核病常见的地区，一些被诊断为涂片阴性肺结核的患者实际上患有诺卡菌病。临床医生应意识到，在接受抗结核治疗无效的HIV/免疫功能低下且患有呼吸道感染的患者中存在这种疾病。
