Anschel David J, Aherne Andrew, Soto Roy G, Carrion Wesley, Hoegerl Carl, Nori Palgun, Seidman Peggy A
Department of Neurology, Stony Brook University Medical Center, Stony Brook, New York, USA.
J Clin Neurophysiol. 2008 Feb;25(1):56-61. doi: 10.1097/WNP.0b013e318163cca6.
Intraoperative neurophysiological monitoring (IONM) during corrective spinal surgery is widely used. Because of the possible interference with the recording of evoked potentials by inhalational anesthetics, total intravenous anesthetic (TIVA) regimens have been advocated. TIVA regimens may be difficult to use in pediatric populations due to metabolic factors. We report on the results of multimodality IONM during 18 cases in which a TIVA regimen incorporating dexmedetomidine (Precedex, Hespira, Lake Forest, IL) was used. Monitoring techniques included sensory (SSEP) and motor evoked potentials (MEP), as well as pedicle screw stimulation. SSEPs were maintained within an acceptable range of baseline amplitude (50%) and latency (10%), and MEPs remained elicitable throughout each case. We therefore found that the anesthetic regimen did not significantly interfere with any of the monitoring modalities used and conclude that IONM in the presence of dexmedetomidine is feasible under appropriate conditions.
脊柱矫正手术中的术中神经生理监测(IONM)被广泛应用。由于吸入性麻醉剂可能干扰诱发电位的记录,因此有人提倡采用全静脉麻醉(TIVA)方案。由于代谢因素,TIVA方案在儿科人群中可能难以应用。我们报告了18例使用含右美托咪定(Precedex,Hespira,伊利诺伊州莱克福里斯特)的TIVA方案的多模式IONM结果。监测技术包括感觉诱发电位(SSEP)和运动诱发电位(MEP),以及椎弓根螺钉刺激。SSEP维持在基线振幅(50%)和潜伏期(10%)的可接受范围内,并且在每个病例中MEP始终可引出。因此,我们发现麻醉方案并未对所使用的任何监测模式产生显著干扰,并得出结论,在适当条件下,使用右美托咪定进行IONM是可行的。