Roman H, Robillard P Y, Hulsey T C, Laffitte A, Kouteich K, Marpeau L, Barau G
Department of Gynaecology et Obstetrics, University Hospital of Rouen, Germont Avenue, 76031 Rouen, France.
West Indian Med J. 2007 Oct;56(5):421-6.
To compare the incidence of antenatal and intrapartum complications and neonatal outcomes among pre-pregnant obese women.
At the Sud-Reunion Hospital's maternity, Reunion Islands, France, over a 54-month period, each obese pregnant woman (BMI > or = 30 kg/m2) delivering a singleton after 22-weeks gestation was compared to the next age and parity-matched woman of normal pre-pregnancy weight (BMI 18.5-25 kg/m2), who delivered after the index case. The Students t test, Mann and Whitney test, Chi-square test and logistic regression model were used for statistical analysis.
The study enrolled 2081 obese women and 2081 controls. The incidences of pre-eclampsia, chronic and pregnancy-induced hypertension, chronic and gestational diabetes mellitus were increased in the obese women group. Prenatal care in obese women required a high rate of hospitalizations as well as a high rate of insulin treatment. Obese women were more likely to be delivered by Caesarean section. The rate of in utero fetal death, neonatal and perinatal death was significantly higher in the obese women group. The high BMI in relation with both pre-eclampsia and in utero fetal death remained unchanged after adjustment of other risk factors.
Obese women were more likely to present several obstetric complications and to be delivered by Caesarean section. Obstetricians who decide on a first Caesarean section in an obese woman should be aware of the cumulated obesity and uterine scar risks that could threaten any subsequent Caesarean section.
比较孕前肥胖女性产前和产时并发症的发生率以及新生儿结局。
在法国留尼汪岛南部留尼汪医院的产科,在54个月的时间里,将每一位妊娠22周后分娩单胎的肥胖孕妇(BMI≥30 kg/m²)与下一位年龄和产次匹配的孕前体重正常(BMI 18.5 - 25 kg/m²)且在该索引病例之后分娩的女性进行比较。采用学生t检验、曼-惠特尼检验、卡方检验和逻辑回归模型进行统计分析。
该研究纳入了2081名肥胖女性和2081名对照。肥胖女性组中先兆子痫、慢性高血压和妊娠高血压、慢性糖尿病和妊娠期糖尿病的发生率增加。肥胖女性的产前护理需要较高的住院率以及较高的胰岛素治疗率。肥胖女性更有可能通过剖宫产分娩。肥胖女性组中宫内胎儿死亡、新生儿和围产儿死亡率显著更高。在调整其他危险因素后,与先兆子痫和宫内胎儿死亡相关的高BMI仍未改变。
肥胖女性更有可能出现多种产科并发症并通过剖宫产分娩。决定对肥胖女性进行首次剖宫产的产科医生应意识到累积的肥胖和子宫瘢痕风险,这些风险可能会威胁到任何后续的剖宫产。