Kopferschmitt-Kubler M C, Bessot J C, Charles P, Blaumeiser-Kapps M, Pauli G
Service de Pneumologie, Pavillon Laennec, CHRU Strasbourg.
Rev Mal Respir. 1991;8(2):240-1.
We report a case of isocyanate induced asthma in a patient who had been previously exposed to isocyanate and had become a porter in a factory producing polyurethene foam. The test for exposure to TDI was positive. The recognition of occupational asthma was nevertheless challenged and the patient was not considered to be carrying out work involving exposure to the inhalation of isocyanates. The effect of a change of job in the development of occupational asthma, and the risk of asthma induced by isocyanates despite inhaled concentrations inferior to the VME, the difficulty of obtaining a recognition of occupational asthma when the working conditions fulfilled do not exactly correspond to those labelled in the schedule for occupational diseases, are discussed in this paper.
我们报告了一例异氰酸酯诱发哮喘的病例，该患者此前曾接触过异氰酸酯，后来成为一家生产聚氨酯泡沫工厂的搬运工。TDI暴露检测呈阳性。然而，职业性哮喘的诊断受到了质疑，该患者未被认为从事涉及吸入异氰酸酯的工作。本文讨论了工作变动在职业性哮喘发病中的作用、尽管吸入浓度低于职业接触限值（VME）但异氰酸酯仍诱发哮喘的风险，以及当工作条件不完全符合职业病目录中所标注的条件时职业性哮喘诊断的困难。
